GAVRIL LUCIAN GHEORGHIEVICI, CORNELIU TRISCA RUSU, ELENA VOICILA, ION MARIUS NAFLIU, ANCA MARIA CIMBRU, SZIDONIA KATALIN TANCZOS TITANIUM DIOXIDE FOR BIOMEDICAL USES I. THE CONTROLLED PRODUCTION OF NANOPARTICLES BY HIDROTHERMAL SYNTHESIS MODERATED BY DIMEDONE The controlled the solvo-hydro-thermal titanium dioxide synthesis moderated by dimedone from organometallic precursors is approached in order to obtain nanoparticles compatible with the polymeric systems used in the dental technique. The experiments carried out with relation to the production of titanium dioxide nanoparticles using the solvo-hydro-thermal synthesis allowed the production of three types of materials by means of varying the nature of the used solvent: methanol, ethanol and propanol (TiO2-M, TiO2-E and TiO2-P).The characterisation using electron microscopy (SEM and HRTEM), X-ray analysis, FTIR and UV-Vis spectrometry show that the diameter of the produced nanoparticles is less than 15 nm and decreases in the order: dpMethanol > dpEthanol > dpPropanol. The nanoparticles contain trace organic substances which the smaller they are, the bigger the alcohol chain used as a solvent is. The adsorption of a target dye showed increasing values with the increasing number of atoms in the hydrocarbon alcohol chain. The highlighted characteristics suggest the possibility of using the synthesised nanoparticles in the production of hard implants for dental reconstruction.