GABRIELA DOROS, CRISTINA OLARIU, ANDRADA MARA ARDELEAN, RAMONA STROESCU, MIHAI GAFENCU RELEVANCE OF THE CARDIAC BIOMARKERS IN CHILDREN WITH HEART DISEASE ADMITTED FOR SEVERE CARDIAC PATHOLOGY Heart disease in children can be congenital or acquired. Most congenital heart malformations have specific hemodynamics, producing either volume overload, pressure overload or both, that will finally determine myocardial cell damage, with complications like heart failure and sometime severe pulmonary hypertension. The understanding and management of pediatric patients with heart disease is mandatory in order to have the ability to influence the outcome. Cardiovascular biomarkers play a vital role in adult cardiology, influencing both the diagnosis and the prognostic, however there is still a gap in the pediatric field. We decided to study the relevance of cardiac biomarkers as: NT proBNP, Troponin T and hs-CRP, in the diagnosis and follow up of the pediatric patients with heart disease admitted for severe acute/chronic symptomes or patology, hoping that in future, cardiac biomarkers will be current used in the assessment of children with heart disease.
Keywords: biomarkers, Troponin, NT-proBNP, hs-CRP, heart disease, children