LUANA ANDREEA MACOVEI, MAGDALENA BIRSAN, VLAD IOAN TEODOR, ANA CATERINA CRISTOFOR, NICOLETA IOANID, ELENA REZUS ON THE ROLE OF CHEMICAL AND MOLECULAR BIOLOGY IN INFLAMMATION RESEARCH Inflammation is an elaborate reflex response of the body to the action of harmful agents. This reaction manifests itself in the form of functional and structural changes of vascular tissues. The inflammatory response is the result of the human evolutionary process. It has three main stages, which are closely related to each other and evolve simultaneously: tissue dystrophy (alteration); impairment of blood circulation (transudation of fluid and migration of leukocytes) and multiplication of cellular elements (proliferation). These phenomena express both a disturbance of biological activity in body tissues and the defense mechanisms to restore the damaged areas. There are two interrelated processes which are often inseparable from each other in the inflammatory response. First, there is the pathological process itself, the tissue damage in form of dystrophy, necrobiosis or necrosis. Second, there is the physiological mechanism of defense, the process of recovery or the physiological response against the disease, manifested as exudation, phagocytosis and proliferation. Simultaneity of both processes is characteristic to inflammatory processes.