Considerations on Thermal Behaviour and Porosity of Renal Calculi in Bisphosphonate -Treated Postmenopausal Women

Tanasescu, Rodica Narcisa; Bardan, Razvan; Ledeti, Adriana; Ledeti, Ionut; Matusz, Petru; Balint, Germaine Savoiu; Bolintineanu, Sorin Lucian

Rodica Narcisa Tanasescu, Razvan Bardan, Adriana Ledeti, Ionut Ledeti, Petru Matusz, Germaine Savoiu Balint, Sorin Lucian Bolintineanu

Considerations on Thermal Behaviour and Porosity of Renal Calculi in Bisphosphonate -Treated Postmenopausal Women

Abstract:

A longitudinal, randomized, five year follow-up clinical and experimental study was conducted during May 1, 2011 - June 30, 2016. A number of 125 eligible postmenopausal women (BMD T-score spine (-2.8 ± 0.5)); BMD at the femoral hip (-2.6 ± 0.8), treated only with biphosphonates, were enrolled in the study. The patient’s age ranged between 60 and 65 years. All the women were stone formers, with more than five episodes of crystalluria in the last five years. Exclusion criteria: kidney chronic diseases, use of drugs known to affect bone metabolism and renal function, patients with multi-morbidities. The aim of our study was to assess the connection between postmenopausal osteoporosis and the risk of worsening calcium balance in urolithiasis, based on the complex thermogravimetric findings and porosity studies of renal stones eliminated by these patients. The study of renal-urinary concretions offers the possibility to amplify the specific effects of the thermal decomposition processes of substances, reflecting the sample’s global composition. The research of calculi porosity gives information about the dissolution possibilities of the renal-urinary concretions. In conclusion, in postmenopausal women, proper administration of bisphosphonate therapy must accompany the supplementary medication with calcium and vitamin D, always correlated to the metabolic status of the osteoporotic patient.

Keywords:
postmenopausal osteoporosis; bone mineral density; biphosphonates; urolithiasis; porosity; Thermogravimetry (TG); Differential Thermal Analysis (DTA)

Issue: 2017, Volume 68, Issue 6

Pages: 1259-1263

Publication date: 2017/7/15

https://doi.org/10.37358/RC.17.6.5653

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Citation Styles

Cite this article as:
TANASESCU, R.N., BARDAN, R., LEDETI, A., LEDETI, I., MATUSZ, P., BALINT, G.S., BOLINTINEANU, S.L., Considerations on Thermal Behaviour and Porosity of Renal Calculi in Bisphosphonate -Treated Postmenopausal Women, Rev. Chim., 68(6), 2017, 1259-1263.

Vancouver
Tanasescu RN, Bardan R, Ledeti A, Ledeti I, Matusz P, Balint GS, Bolintineanu SL. Considerations on Thermal Behaviour and Porosity of Renal Calculi in Bisphosphonate -Treated Postmenopausal Women. Rev. Chim.[internet]. 2017 Jun;68(6):1259-1263. Available from: https://doi.org/10.37358/RC.17.6.5653

APA 6th edition
Tanasescu, R.N., Bardan, R., Ledeti, A., Ledeti, I., Matusz, P., Balint, G.S. & Bolintineanu, S.L. (2017). Considerations on Thermal Behaviour and Porosity of Renal Calculi in Bisphosphonate -Treated Postmenopausal Women. Revista de Chimie, 68(6), 1259-1263. https://doi.org/10.37358/RC.17.6.5653

Harvard
Tanasescu, R.N., Bardan, R., Ledeti, A., Ledeti, I., Matusz, P., Balint, G.S., Bolintineanu, S.L. (2017). 'Considerations on Thermal Behaviour and Porosity of Renal Calculi in Bisphosphonate -Treated Postmenopausal Women', Revista de Chimie, 68(6), pp. 1259-1263. https://doi.org/10.37358/RC.17.6.5653

IEEE
R.N. Tanasescu, R. Bardan, A. Ledeti, I. Ledeti, P. Matusz, G.S. Balint, S.L. Bolintineanu, "Considerations on Thermal Behaviour and Porosity of Renal Calculi in Bisphosphonate -Treated Postmenopausal Women". Revista de Chimie, vol. 68, no. 6, pp. 1259-1263, 2017. [online]. https://doi.org/10.37358/RC.17.6.5653

Text
Rodica Narcisa Tanasescu, Razvan Bardan, Adriana Ledeti, Ionut Ledeti, Petru Matusz, Germaine Savoiu Balint, Sorin Lucian Bolintineanu,
Considerations on Thermal Behaviour and Porosity of Renal Calculi in Bisphosphonate -Treated Postmenopausal Women,
Revista de Chimie,
Volume 68, Issue 6,
2017,
Pages 1259-1263,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.6.5653.
(https://revistadechimie.ro/Articles.asp?ID=5653)
Keywords: postmenopausal osteoporosis; bone mineral density; biphosphonates; urolithiasis; porosity; Thermogravimetry (TG); Differential Thermal Analysis (DTA)

RIS
TY - JOUR
T1 - Considerations on Thermal Behaviour and Porosity of Renal Calculi in Bisphosphonate -Treated Postmenopausal Women
A1 - Tanasescu, Rodica Narcisa
A2 - Bardan, Razvan
A3 - Ledeti, Adriana
A4 - Ledeti, Ionut
A5 - Matusz, Petru
A6 - Balint, Germaine Savoiu
A7 - Bolintineanu, Sorin Lucian
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 6
SP - 1259
EP - 1263
UR - https://doi.org/10.37358/RC.17.6.5653
KW - postmenopausal osteoporosis
KW - bone mineral density
KW - biphosphonates
KW - urolithiasis
KW - porosity
KW - Thermogravimetry (TG)
KW - Differential Thermal Analysis (DTA)
ER -

BibTex
@article{RevCh2017P1259,
author = {Tanasescu Rodica Narcisa and Bardan Razvan and Ledeti Adriana and Ledeti Ionut and Matusz Petru and Balint Germaine Savoiu and Bolintineanu Sorin Lucian},
title = {Considerations on Thermal Behaviour and Porosity of Renal Calculi in Bisphosphonate -Treated Postmenopausal Women},
journal = {Revista de Chimie},
volume = {68},
number = {6},
pages = {1259-1263},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.6.5653},
url = {https://revistadechimie.ro/Articles.asp?ID=5653}
}

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