Dental Development in Children After Chemotherapy

Bica, Cristina; Chincesan, Mihaela; Esian, Daniela; Martha, Krisztina; Ion, Valentin; Marinescu, Larisa Andreea; Earar, Kamel; Matei, Madalina Nicoleta

Cristina Bica, Mihaela Chincesan, Daniela Esian, Krisztina Martha, Valentin Ion, Larisa Andreea Marinescu, Kamel Earar, Madalina Nicoleta Matei

Dental Development in Children After Chemotherapy

Abstract:

Chemotherapy, as a treatment method in paediatric oncology, coincides with the physiological process of tooth development. The interference between cytostatic agents and the cycle of the cells with specialised functions in the formation and mineralisation of dental structures leads to the appearance of abnormalities in the development of the tooth buds, structural defects and disorderly eruption. We have looked into the distribution of developmental tooth disorders in a group of children suffering from malignant ailments. The study reveals a high occurrence of microdontia and agenesis of premolars among children diagnosed with high-risk acute lymphoblastic leukemia at the age between 1 and 6, as well as tooth eruption disturbances in 70% of the children. The nature and the severity of dental abnormalities depend on the type of cytostatic medication, the dosage and the frequency of therapeutic cycles, the age of the child at the beginning of the oncological therapy, as well as on the stage of the odontogenesis.

Keywords:
chemotherapy; leukemia; dental development

Issue: 2017, Volume 68, Issue 6

Pages: 1397-1400

Publication date: 2017/7/15

https://doi.org/10.37358/RC.17.6.5681

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BICA, C., CHINCESAN, M., ESIAN, D., MARTHA, K., ION, V., MARINESCU, L.A., EARAR, K., MATEI, M.N., Dental Development in Children After Chemotherapy, Rev. Chim., 68(6), 2017, 1397-1400.

Vancouver
Bica C, Chincesan M, Esian D, Martha K, Ion V, Marinescu LA, Earar K, Matei MN. Dental Development in Children After Chemotherapy. Rev. Chim.[internet]. 2017 Jun;68(6):1397-1400. Available from: https://doi.org/10.37358/RC.17.6.5681

APA 6th edition
Bica, C., Chincesan, M., Esian, D., Martha, K., Ion, V., Marinescu, L.A., Earar, K. & Matei, M.N. (2017). Dental Development in Children After Chemotherapy. Revista de Chimie, 68(6), 1397-1400. https://doi.org/10.37358/RC.17.6.5681

Harvard
Bica, C., Chincesan, M., Esian, D., Martha, K., Ion, V., Marinescu, L.A., Earar, K., Matei, M.N. (2017). 'Dental Development in Children After Chemotherapy', Revista de Chimie, 68(6), pp. 1397-1400. https://doi.org/10.37358/RC.17.6.5681

IEEE
C. Bica, M. Chincesan, D. Esian, K. Martha, V. Ion, L.A. Marinescu, K. Earar, M.N. Matei, "Dental Development in Children After Chemotherapy". Revista de Chimie, vol. 68, no. 6, pp. 1397-1400, 2017. [online]. https://doi.org/10.37358/RC.17.6.5681

Text
Cristina Bica, Mihaela Chincesan, Daniela Esian, Krisztina Martha, Valentin Ion, Larisa Andreea Marinescu, Kamel Earar, Madalina Nicoleta Matei,
Dental Development in Children After Chemotherapy,
Revista de Chimie,
Volume 68, Issue 6,
2017,
Pages 1397-1400,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.6.5681.
(https://revistadechimie.ro/Articles.asp?ID=5681)
Keywords: chemotherapy; leukemia; dental development

RIS
TY - JOUR
T1 - Dental Development in Children After Chemotherapy
A1 - Bica, Cristina
A2 - Chincesan, Mihaela
A3 - Esian, Daniela
A4 - Martha, Krisztina
A5 - Ion, Valentin
A6 - Marinescu, Larisa Andreea
A7 - Earar, Kamel
A8 - Matei, Madalina Nicoleta
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 6
SP - 1397
EP - 1400
UR - https://doi.org/10.37358/RC.17.6.5681
KW - chemotherapy
KW - leukemia
KW - dental development
ER -

BibTex
@article{RevCh2017P1397,
author = {Bica Cristina and Chincesan Mihaela and Esian Daniela and Martha Krisztina and Ion Valentin and Marinescu Larisa Andreea and Earar Kamel and Matei Madalina Nicoleta},
title = {Dental Development in Children After Chemotherapy},
journal = {Revista de Chimie},
volume = {68},
number = {6},
pages = {1397-1400},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.6.5681},
url = {https://revistadechimie.ro/Articles.asp?ID=5681}
}

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