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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2017, Volume 68, Issue 7, 1636-1639

https://doi.org/10.37358/RC.17.7.5733

Dan Navolan, Simona Vladareanu, Ioana Ciohat, Adrian Carabineanu, Marius Craina, Dragos Nemescu, Bogdan Birsasteanu, Alina Onofriescu, Marioara Boia, Efstathios Tepetzikiotis, Mihaela Craciunescu, Florin Birsasteanu

Distribution of Biochemical and Ultrasound Markers Values in the First Trimester Screening Program in Timisoara

Abstract:

The aim of our study was to analyze the distribution of biochemical markers (free-â hCG and PAPP-A) and nuchal translucency (NT) values and their deviation from expected median in our screening program. NT, free-â hCG and PAPP-A values were measured in first trimester sera of 1313 singleton pregnant women. The age (mean ±standard deviation) of pregnant women at the time of screening was 28.94±4.95 years and the gestational age was 87.66±4.74 days. The value of NT (median±standard error of mean) was 0.87±0.01 multiple of median corrected (MoMc), of free-b hCG was 1.07±0.02 MoMc and of PAPP-A was 1.06±0.01 MoMc. Since the huge majority of pregnant women carried a healthy fetus it was assumed that the median value of measurements was equal to 1 MoMc and the deviation from median was equal to null. Our results showed that the greatest deviation from the expected median (-0.13 MoMc) was recorded for the NT measurement while the deviation for the free-â hCG and PAPP-A values was 0.07 respectively 0.06. In conclusion the main disturbing factor in calculating the aneuploidy risk was the measurement of NT. A systematic audit of laboratory and ultrasound measurement is necessary.
Keywords:
first trimester screening; aneuploidies; deviation from median; audit

Issue: 2017, Volume 68, Issue 7
Pages: 1636-1639
Publication date: 2017/8/15
https://doi.org/10.37358/RC.17.7.5733
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
NAVOLAN, D., VLADAREANU, S., CIOHAT, I., CARABINEANU, A., CRAINA, M., NEMESCU, D., BIRSASTEANU, B., ONOFRIESCU, A., BOIA, M., TEPETZIKIOTIS, E., CRACIUNESCU, M., BIRSASTEANU, F., Distribution of Biochemical and Ultrasound Markers Values in the First Trimester Screening Program in Timisoara, Rev. Chim., 68(7), 2017, 1636-1639.

Vancouver
Navolan D, Vladareanu S, Ciohat I, Carabineanu A, Craina M, Nemescu D, Birsasteanu B, Onofriescu A, Boia M, Tepetzikiotis E, Craciunescu M, Birsasteanu F. Distribution of Biochemical and Ultrasound Markers Values in the First Trimester Screening Program in Timisoara. Rev. Chim.[internet]. 2017 Jul;68(7):1636-1639. Available from: https://doi.org/10.37358/RC.17.7.5733


APA 6th edition
Navolan, D., Vladareanu, S., Ciohat, I., Carabineanu, A., Craina, M., Nemescu, D.,... Birsasteanu, F. (2017). Distribution of Biochemical and Ultrasound Markers Values in the First Trimester Screening Program in Timisoara. Revista de Chimie, 68(7), 1636-1639. https://doi.org/10.37358/RC.17.7.5733


Harvard
Navolan, D., Vladareanu, S., Ciohat, I., Carabineanu, A., Craina, M., Nemescu, D., Birsasteanu, B., Onofriescu, A., Boia, M., Tepetzikiotis, E., Craciunescu, M., Birsasteanu, F. (2017). 'Distribution of Biochemical and Ultrasound Markers Values in the First Trimester Screening Program in Timisoara', Revista de Chimie, 68(7), pp. 1636-1639. https://doi.org/10.37358/RC.17.7.5733


IEEE
D. Navolan, S. Vladareanu, I. Ciohat, A. Carabineanu, M. Craina, D. Nemescu, B. Birsasteanu, A. Onofriescu, M. Boia, E. Tepetzikiotis, M. Craciunescu, F. Birsasteanu, "Distribution of Biochemical and Ultrasound Markers Values in the First Trimester Screening Program in Timisoara". Revista de Chimie, vol. 68, no. 7, pp. 1636-1639, 2017. [online]. https://doi.org/10.37358/RC.17.7.5733


Text
Dan Navolan, Simona Vladareanu, Ioana Ciohat, Adrian Carabineanu, Marius Craina, Dragos Nemescu, Bogdan Birsasteanu, Alina Onofriescu, Marioara Boia, Efstathios Tepetzikiotis, Mihaela Craciunescu, Florin Birsasteanu,
Distribution of Biochemical and Ultrasound Markers Values in the First Trimester Screening Program in Timisoara,
Revista de Chimie,
Volume 68, Issue 7,
2017,
Pages 1636-1639,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.7.5733.
(https://revistadechimie.ro/Articles.asp?ID=5733)
Keywords: first trimester screening; aneuploidies; deviation from median; audit


RIS
TY - JOUR
T1 - Distribution of Biochemical and Ultrasound Markers Values in the First Trimester Screening Program in Timisoara
A1 - Navolan, Dan
A2 - Vladareanu, Simona
A3 - Ciohat, Ioana
A4 - Carabineanu, Adrian
A5 - Craina, Marius
A6 - Nemescu, Dragos
A7 - Birsasteanu, Bogdan
A8 - Onofriescu, Alina
A9 - Boia, Marioara
A10 - Tepetzikiotis, Efstathios
A11 - Craciunescu, Mihaela
A12 - Birsasteanu, Florin
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 7
SP - 1636
EP - 1639
UR - https://doi.org/10.37358/RC.17.7.5733
KW - first trimester screening
KW - aneuploidies
KW - deviation from median
KW - audit
ER -


BibTex
@article{RevCh2017P1636,
author = {Navolan Dan and Vladareanu Simona and Ciohat Ioana and Carabineanu Adrian and Craina Marius and Nemescu Dragos and Birsasteanu Bogdan and Onofriescu Alina and Boia Marioara and Tepetzikiotis Efstathios and Craciunescu Mihaela and Birsasteanu Florin},
title = {Distribution of Biochemical and Ultrasound Markers Values in the First Trimester Screening Program in Timisoara},
journal = {Revista de Chimie},
volume = {68},
number = {7},
pages = {1636-1639},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.7.5733},
url = {https://revistadechimie.ro/Articles.asp?ID=5733}
}
 
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