CLAUDIA CRINA TOMA, TERESA CASACCHIA, IOAN DON, CLAUDIA D'IPPOLITO, GIANCARLO STATTI NEW EXTRACTION TECHNOLOGIES FOR SYRINGA VULGARIS (OLEACEAE) MERISTEMATIC EXTRACTS The use of meristematic tissues for the production of health-related extracts (meristemotherapy) is coded by the european pharmacopoeia. However, traditional macerated glycerol requires long production times, based on classical extraction by diffusion. The use of a Dynamic Extraction Accelerator (Naviglio® Extractor) allowed for extraction in significantly faster (6 h) times compared to the conventional ones for the preparation of a macerated glycerol (21 days). The quantitative results of extracting Syringa vulgaris meristematic tissues were measured in terms of the amount of total extracted polyphenols and total extracted flavonoids. The biological activity related to the inhibition of the pancreatic lipase enzyme was compared and, as expected, looking phytochemical composition, the extract IC50 in Naviglio® Extractor was significantly lower than that of macerated glycerol.
Keywords: meristematic, gemmotherapic, lipase pancreatic, total phenolic