ELENA LACRAMIOARA LISA, GETA CARAC, VASILICA BARBU, SILVIA ROBU THE SYNERGISTIC ANTIOXIDANT EFFECT AND ANTIMICROBIAL EFFICACITY OF PROPOLIS, MYRRH AND CHLORHEXIDINE AS BENEFICIAL TOOTHPASTE COMPONENTS Toothpastes containing different components which could have beneficial effects on oral health and the identification of better composition are always a research challenge. Our study aims are to evaluate the synergistic effect of propolis, myrrh, and chlorhexidine, separated and combined in some formulated toothpaste. To assess the electrochemical capacity by monitoring of physico-chemical parameters (pH conductivity), the mixture of these components in toothpaste into artificial saliva solution was performed in ambient medium and at 37oC. The antioxidant activity and the antimicrobial potential in vitro of toothpastes formulated against microorganisms that frequently colonize the oral cavity was performed also. It has been found that mixtures of chlorhexidine, propolis, and myrrh exhibit synergistic antioxidant activity with better potential than some commercial toothpaste, also the antibacterial activity shown that this activity is maintained in time against some strains.