The Effect of Chemical Compounds from Cigarettes Smoke on First Trimester Biochemical Markers

Carabineanu, Adrian; Navolan, Dan; Birsasteanu, Florin; Cretu, Octavian; Boia, Marioara; Craina, Marius; Badiu, Diana Liana; Ionescu, Crangu Antoniu; Mehedintu, Claudia; Vladareanu, Simona; Ciohat, Ioana; Craciunescu, Mihaela; Nemescu, Dragos

Adrian Carabineanu, Dan Navolan, Florin Birsasteanu, Octavian Cretu, Marioara Boia, Marius Craina, Diana Liana Badiu, Crangu Antoniu Ionescu, Claudia Mehedintu, Simona Vladareanu, Ioana Ciohat, Mihaela Craciunescu, Dragos Nemescu

The Effect of Chemical Compounds from Cigarettes Smoke on First Trimester Biochemical Markers

Abstract:

Previous studies showed that certain behavioral and physical parameters influence the concentration of first trimester biochemical markers. The scope of the present article was to study the relationship between smoking and first trimester screening biochemical markers and the capability of the software to counterbalance this influence. Concentrations of pregnancy-associated protein A (PAPP-A) and free b chorionic gonadotropin hormone (free b hCG) were measured in sera of 1554 first trimester pregnant women, 1349 of which were non-smokers and 205 were smokers. First trimester PAPP-A values are lower in smoking compared to non-smoking pregnant women (0.94±0.04 vs. 1.09±0.02, p=0.0004), since smoking seems not to influence free b hCG concentration (1.11±0.07 vs. 1.03±0.02, ns). The software used by us corrected successfully the effect of chemical compounds from cigarette smoke on PAPP-A values.

Keywords:
PAPP-A; free b hCG; first trimester biochemical markers; aneuploidies; smoking; software correction

Issue: 2017, Volume 68, Issue 9

Pages: 2122-2124

Publication date: 2017/10/15

https://doi.org/10.37358/RC.17.9.5837

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CARABINEANU, A., NAVOLAN, D., BIRSASTEANU, F., CRETU, O., BOIA, M., CRAINA, M., BADIU, D.L., IONESCU, C.A., MEHEDINTU, C., VLADAREANU, S., CIOHAT, I., CRACIUNESCU, M., NEMESCU, D., The Effect of Chemical Compounds from Cigarettes Smoke on First Trimester Biochemical Markers, Rev. Chim., 68(9), 2017, 2122-2124.

Vancouver
Carabineanu A, Navolan D, Birsasteanu F, Cretu O, Boia M, Craina M, Badiu DL, Ionescu CA, Mehedintu C, Vladareanu S, Ciohat I, Craciunescu M, Nemescu D. The Effect of Chemical Compounds from Cigarettes Smoke on First Trimester Biochemical Markers. Rev. Chim.[internet]. 2017 Sep;68(9):2122-2124. Available from: https://doi.org/10.37358/RC.17.9.5837

APA 6th edition
Carabineanu, A., Navolan, D., Birsasteanu, F., Cretu, O., Boia, M., Craina, M.,... Nemescu, D. (2017). The Effect of Chemical Compounds from Cigarettes Smoke on First Trimester Biochemical Markers. Revista de Chimie, 68(9), 2122-2124. https://doi.org/10.37358/RC.17.9.5837

Harvard
Carabineanu, A., Navolan, D., Birsasteanu, F., Cretu, O., Boia, M., Craina, M., Badiu, D.L., Ionescu, C.A., Mehedintu, C., Vladareanu, S., Ciohat, I., Craciunescu, M., Nemescu, D. (2017). 'The Effect of Chemical Compounds from Cigarettes Smoke on First Trimester Biochemical Markers', Revista de Chimie, 68(9), pp. 2122-2124. https://doi.org/10.37358/RC.17.9.5837

IEEE
A. Carabineanu, D. Navolan, F. Birsasteanu, O. Cretu, M. Boia, M. Craina, D.L. Badiu, C.A. Ionescu, C. Mehedintu, S. Vladareanu, I. Ciohat, M. Craciunescu, D. Nemescu, "The Effect of Chemical Compounds from Cigarettes Smoke on First Trimester Biochemical Markers". Revista de Chimie, vol. 68, no. 9, pp. 2122-2124, 2017. [online]. https://doi.org/10.37358/RC.17.9.5837

Text
Adrian Carabineanu, Dan Navolan, Florin Birsasteanu, Octavian Cretu, Marioara Boia, Marius Craina, Diana Liana Badiu, Crangu Antoniu Ionescu, Claudia Mehedintu, Simona Vladareanu, Ioana Ciohat, Mihaela Craciunescu, Dragos Nemescu,
The Effect of Chemical Compounds from Cigarettes Smoke on First Trimester Biochemical Markers,
Revista de Chimie,
Volume 68, Issue 9,
2017,
Pages 2122-2124,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.9.5837.
(https://revistadechimie.ro/Articles.asp?ID=5837)
Keywords: PAPP-A; free b hCG; first trimester biochemical markers; aneuploidies; smoking; software correction

RIS
TY - JOUR
T1 - The Effect of Chemical Compounds from Cigarettes Smoke on First Trimester Biochemical Markers
A1 - Carabineanu, Adrian
A2 - Navolan, Dan
A3 - Birsasteanu, Florin
A4 - Cretu, Octavian
A5 - Boia, Marioara
A6 - Craina, Marius
A7 - Badiu, Diana Liana
A8 - Ionescu, Crangu Antoniu
A9 - Mehedintu, Claudia
A10 - Vladareanu, Simona
A11 - Ciohat, Ioana
A12 - Craciunescu, Mihaela
A13 - Nemescu, Dragos
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 9
SP - 2122
EP - 2124
UR - https://doi.org/10.37358/RC.17.9.5837
KW - PAPP-A
KW - free b hCG
KW - first trimester biochemical markers
KW - aneuploidies
KW - smoking
KW - software correction
ER -

BibTex
@article{RevCh2017P2122,
author = {Carabineanu Adrian and Navolan Dan and Birsasteanu Florin and Cretu Octavian and Boia Marioara and Craina Marius and Badiu Diana Liana and Ionescu Crangu Antoniu and Mehedintu Claudia and Vladareanu Simona and Ciohat Ioana and Craciunescu Mihaela and Nemescu Dragos},
title = {The Effect of Chemical Compounds from Cigarettes Smoke on First Trimester Biochemical Markers},
journal = {Revista de Chimie},
volume = {68},
number = {9},
pages = {2122-2124},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.9.5837},
url = {https://revistadechimie.ro/Articles.asp?ID=5837}
}

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