Lipid Profiles and Framingham Risk Score in Patients with Coronary Artery Bypass Graft Surgery undergoing Cardiac Rehabilitation Program

Namat, Razan Al; Costache, Irina Iuliana; Felea, Maura Gabriela; Petris, Antoniu; Aursulesei, Viviana; Mitu, Ovidiu; Namat, Nadia Al; Namat, Dina Al; Constantin, Mihai; Mitu, Florin

Razan Al Namat, Irina Iuliana Costache, Maura Gabriela Felea, Antoniu Petris, Viviana Aursulesei, Ovidiu Mitu, Nadia Al Namat, Dina Al Namat, Mihai Constantin, Florin Mitu

Lipid Profiles and Framingham Risk Score in Patients with Coronary Artery Bypass Graft Surgery undergoing Cardiac Rehabilitation Program

Abstract:

Coronary artery disease (CAD) is one of the major predictors of future cardiovascular events (CVEs). In addition, biomarkers such as high-sensitivity C-Reactive Protein (hsCRP), fibrinogen, homocysteine, and free fatty acid (FFA) correlate well with a future CVE. The Framingham Risk Score is a gender-specific algorithm used to estimate the 10-year cardiovascular risk of an individual. Cardiac rehabilitation is an instrument of medical management in cardiovascular diseases; beyond prevention, it can improve heart and muscle functioning in patients that were undergoing CABG, and cardiac and vascular adaptation. Over a 2-year period, 120 subjects were randomized and comprehensively evaluated. The mean age of the patients under study was 65.70 ± 9.91 years old. For the Framingham cardiovascular risk score, the mean value in the Phase I was 16.5, while the mean value in Phase III was 10.6. The difference registered after cardiac surgery and the value in 6 months after the onset of cardiac rehabilitation program was important and statistically significant, as p [ 0.05. Fibrinogen showed significant phase-to-phase reductions of plasmatic values. Lipid profile values showed a statistically significant decrease. The renal filtration function evaluated by plasma creatinine showed statistically significant improvement and, in terms of absolute values, creatinine level was reduced in a range between 0.2-0.4 mg/dL. Also, it was recorded a significantly lower level of blood urea. By comparing the Phase I and Phase III results, we observed that the median 10-year Framingham cardiovascular risk score was approximately 6% lower (p [0.05), reflecting the survival benefit gained by patients under the intensive cardiovascular recovery program.

Keywords:
Framingham Risk Score; coronary-artery bypass graft; cardiac rehabilitation

Issue: 2017, Volume 68, Issue 10

Pages: 2219-2223

Publication date: 2017/11/15

https://doi.org/10.37358/RC.17.10.5859

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
NAMAT, R.A., COSTACHE, I.I., FELEA, M.G., PETRIS, A., AURSULESEI, V., MITU, O., NAMAT, N.A., NAMAT, D.A., CONSTANTIN, M., MITU, F., Lipid Profiles and Framingham Risk Score in Patients with Coronary Artery Bypass Graft Surgery undergoing Cardiac Rehabilitation Program, Rev. Chim., 68(10), 2017, 2219-2223.

Vancouver
Namat RA, Costache II, Felea MG, Petris A, Aursulesei V, Mitu O, Namat NA, Namat DA, Constantin M, Mitu F. Lipid Profiles and Framingham Risk Score in Patients with Coronary Artery Bypass Graft Surgery undergoing Cardiac Rehabilitation Program. Rev. Chim.[internet]. 2017 Oct;68(10):2219-2223. Available from: https://doi.org/10.37358/RC.17.10.5859

APA 6th edition
Namat, R.A., Costache, I.I., Felea, M.G., Petris, A., Aursulesei, V., Mitu, O.,... Mitu, F. (2017). Lipid Profiles and Framingham Risk Score in Patients with Coronary Artery Bypass Graft Surgery undergoing Cardiac Rehabilitation Program. Revista de Chimie, 68(10), 2219-2223. https://doi.org/10.37358/RC.17.10.5859

Harvard
Namat, R.A., Costache, I.I., Felea, M.G., Petris, A., Aursulesei, V., Mitu, O., Namat, N.A., Namat, D.A., Constantin, M., Mitu, F. (2017). 'Lipid Profiles and Framingham Risk Score in Patients with Coronary Artery Bypass Graft Surgery undergoing Cardiac Rehabilitation Program', Revista de Chimie, 68(10), pp. 2219-2223. https://doi.org/10.37358/RC.17.10.5859

IEEE
R.A. Namat, I.I. Costache, M.G. Felea, A. Petris, V. Aursulesei, O. Mitu, N.A. Namat, D.A. Namat, M. Constantin, F. Mitu, "Lipid Profiles and Framingham Risk Score in Patients with Coronary Artery Bypass Graft Surgery undergoing Cardiac Rehabilitation Program". Revista de Chimie, vol. 68, no. 10, pp. 2219-2223, 2017. [online]. https://doi.org/10.37358/RC.17.10.5859

Text
Razan Al Namat, Irina Iuliana Costache, Maura Gabriela Felea, Antoniu Petris, Viviana Aursulesei, Ovidiu Mitu, Nadia Al Namat, Dina Al Namat, Mihai Constantin, Florin Mitu,
Lipid Profiles and Framingham Risk Score in Patients with Coronary Artery Bypass Graft Surgery undergoing Cardiac Rehabilitation Program,
Revista de Chimie,
Volume 68, Issue 10,
2017,
Pages 2219-2223,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.10.5859.
(https://revistadechimie.ro/Articles.asp?ID=5859)
Keywords: Framingham Risk Score; coronary-artery bypass graft; cardiac rehabilitation

RIS
TY - JOUR
T1 - Lipid Profiles and Framingham Risk Score in Patients with Coronary Artery Bypass Graft Surgery undergoing Cardiac Rehabilitation Program
A1 - Namat, Razan Al
A2 - Costache, Irina Iuliana
A3 - Felea, Maura Gabriela
A4 - Petris, Antoniu
A5 - Aursulesei, Viviana
A6 - Mitu, Ovidiu
A7 - Namat, Nadia Al
A8 - Namat, Dina Al
A9 - Constantin, Mihai
A10 - Mitu, Florin
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 10
SP - 2219
EP - 2223
UR - https://doi.org/10.37358/RC.17.10.5859
KW - Framingham Risk Score
KW - coronary-artery bypass graft
KW - cardiac rehabilitation
ER -

BibTex
@article{RevCh2017P2219,
author = {Namat Razan Al and Costache Irina Iuliana and Felea Maura Gabriela and Petris Antoniu and Aursulesei Viviana and Mitu Ovidiu and Namat Nadia Al and Namat Dina Al and Constantin Mihai and Mitu Florin},
title = {Lipid Profiles and Framingham Risk Score in Patients with Coronary Artery Bypass Graft Surgery undergoing Cardiac Rehabilitation Program},
journal = {Revista de Chimie},
volume = {68},
number = {10},
pages = {2219-2223},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.10.5859},
url = {https://revistadechimie.ro/Articles.asp?ID=5859}
}

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