ABOUT INDEXING BOARD ARCHIVES AUTHOR GUIDELINES SUBMIT PAPER AUTHOR'S PAGE NEWS, EVENTS CONTACT
REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
ISSN Online 2668-8212
ISSN Print: 1582-9049
ISSN-L: 1582-9049

REVISTA DE CHIMIE Latest Issue

LATEST ISSUE >>>

   Volume 75, 2024
   Volume 74, 2023
   Volume 73, 2022
   Volume 72, 2021
   Volume 71, 2020
   Volume 70, 2019
   Volume 69, 2018
   Volume 68, 2017
   Volume 67, 2016
   Volume 66, 2015
   Volume 65, 2014
   Volume 64, 2013
   Volume 63, 2012
   Volume 62, 2011
   Volume 61, 2010
   Volume 60, 2009
   Volume 59, 2008
   Volume 58, 2007
 
<<<< back

Revista de Chimie (Rev. Chim.), Year 2017, Volume 68, Issue 10, 2320-2324

https://doi.org/10.37358/RC.17.10.5877

Mariana Mateescu, Sanda Maria Doncea, Irina Chican, Cristina Lavinia Nistor, Ioneta Codrina Bujanca

Synthesis of Calcium Carbonate Micro Particles using Emulsion Membrane Process Applied for Drug Release Studies

Abstract:

The aim of this work is the synthesis of calcium carbonate (CaCO3) nano and microparticles and their application as biomaterials (vehicles) for the sustained release of doxycycline. CaCO3 micro particles were synthesized by water-in oil (W/O) emulsion method using emulsion liquid membranes with bis (2-ethylhexyl) phosphate (D2EHPA) as carrier, Span 80 as surfactant, and toluene and kerosene as organic solvents. The aqueous phases contained 1 M CaCl2, and 1 M Na2CO3, respectively. The Dynamic Light Scattering (DLS) data showed CaCO3 particles with sizes ranging from around 100 nm to 3500 nm. The CaCO3 particles with the average diameters around 600 nm attained an adsorbtion of doxycycline of maximum 97.9%, and a slow and steady release with a cumulative value of approximative 50% after ten days.
Keywords:
calcium carbonate; nano and micro particles; doxycycline; drug release

Issue: 2017, Volume 68, Issue 10
Pages: 2320-2324
Publication date: 2017/11/15
https://doi.org/10.37358/RC.17.10.5877
download pdf   Download Pdf Article
Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
MATEESCU, M., DONCEA, S.M., CHICAN, I., NISTOR, C.L., BUJANCA, I.C., Synthesis of Calcium Carbonate Micro Particles using Emulsion Membrane Process Applied for Drug Release Studies, Rev. Chim., 68(10), 2017, 2320-2324.

Vancouver
Mateescu M, Doncea SM, Chican I, Nistor CL, Bujanca IC. Synthesis of Calcium Carbonate Micro Particles using Emulsion Membrane Process Applied for Drug Release Studies. Rev. Chim.[internet]. 2017 Oct;68(10):2320-2324. Available from: https://doi.org/10.37358/RC.17.10.5877


APA 6th edition
Mateescu, M., Doncea, S.M., Chican, I., Nistor, C.L. & Bujanca, I.C. (2017). Synthesis of Calcium Carbonate Micro Particles using Emulsion Membrane Process Applied for Drug Release Studies. Revista de Chimie, 68(10), 2320-2324. https://doi.org/10.37358/RC.17.10.5877


Harvard
Mateescu, M., Doncea, S.M., Chican, I., Nistor, C.L., Bujanca, I.C. (2017). 'Synthesis of Calcium Carbonate Micro Particles using Emulsion Membrane Process Applied for Drug Release Studies', Revista de Chimie, 68(10), pp. 2320-2324. https://doi.org/10.37358/RC.17.10.5877


IEEE
M. Mateescu, S.M. Doncea, I. Chican, C.L. Nistor, I.C. Bujanca, "Synthesis of Calcium Carbonate Micro Particles using Emulsion Membrane Process Applied for Drug Release Studies". Revista de Chimie, vol. 68, no. 10, pp. 2320-2324, 2017. [online]. https://doi.org/10.37358/RC.17.10.5877


Text
Mariana Mateescu, Sanda Maria Doncea, Irina Chican, Cristina Lavinia Nistor, Ioneta Codrina Bujanca,
Synthesis of Calcium Carbonate Micro Particles using Emulsion Membrane Process Applied for Drug Release Studies,
Revista de Chimie,
Volume 68, Issue 10,
2017,
Pages 2320-2324,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.10.5877.
(https://revistadechimie.ro/Articles.asp?ID=5877)
Keywords: calcium carbonate; nano and micro particles; doxycycline; drug release


RIS
TY - JOUR
T1 - Synthesis of Calcium Carbonate Micro Particles using Emulsion Membrane Process Applied for Drug Release Studies
A1 - Mateescu, Mariana
A2 - Doncea, Sanda Maria
A3 - Chican, Irina
A4 - Nistor, Cristina Lavinia
A5 - Bujanca, Ioneta Codrina
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 10
SP - 2320
EP - 2324
UR - https://doi.org/10.37358/RC.17.10.5877
KW - calcium carbonate
KW - nano and micro particles
KW - doxycycline
KW - drug release
ER -


BibTex
@article{RevCh2017P2320,
author = {Mateescu Mariana and Doncea Sanda Maria and Chican Irina and Nistor Cristina Lavinia and Bujanca Ioneta Codrina},
title = {Synthesis of Calcium Carbonate Micro Particles using Emulsion Membrane Process Applied for Drug Release Studies},
journal = {Revista de Chimie},
volume = {68},
number = {10},
pages = {2320-2324},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.10.5877},
url = {https://revistadechimie.ro/Articles.asp?ID=5877}
}
 
<<<< back
 
PUBLISHING SECTION
Author Guidelines
 * Paper Drafting
 * Paper Template
 * Ethical Statement
 * Paper Submission
Ghidul Autorului (ro)
Submit Paper
Author's Page
Publishing Ethics
Peer Review Process
Open Access & Archiving Policy
 Search Authors
 LATEST NEWS
REvista de Chimie NUMAR OMAGIAL PETRU PONI.. detalii
REvista de Chimie Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
dictionar English-Romanian Dictionary for Mechanical Engineering
(download pdf)
  News, Events
Crossref Member Badge
 DOI  logo
 Gold Open Access | Source=http://www.plos.org/  | Author=art designer at PLoS
Creative Commons License
 Conferences of Contemporary
 Chemistry
 Biblioteca Chimiei
 Materiale Plastice