Self-assembled Nanomaterials Type Layered Double Hydroxides Antibiotics Used as Drug Delivery Vectors

Duceac, Letitia Doina; Stafie, Liviu; Banu, Elena Ariela; Paduraru, Oana; Calin, Gabriela; Ciuhodaru, Madalina Irina

Letitia Doina Duceac, Liviu Stafie, Elena Ariela Banu, Oana Paduraru, Gabriela Calin, Madalina Irina Ciuhodaru

Self-assembled Nanomaterials Type Layered Double Hydroxides Antibiotics Used as Drug Delivery Vectors

Abstract:

Due to their biocompatibility, nanomaterials type layered double hydroxides (LDHs) development has attracted many researchers attention especially in medical area using them as drug delivery vectors. Their efficiency is due to the drug controlled release from the interlayer space of LDHs matrices. The controlled drug delivery characteristic is due to the reduction of drug concentration variations and maintains the desired level of drug concentration for long time. Furthermore, this action limits adverse effects and reduces the therapy duration, enhancing bactericidal activity and leading to an effective treatment. This work highlights the synthesis and characterization of hybrid structures type LDHs- tobramycin having application as antibacterial factor against Pseudomonas aeruginosa. The obtained self-assembled structures were morphologically characterized in order to point out the drug-interlayered products. Results indicate superior properties of MgAlLDHs and ZnAlLDHs behaving as host for a wide variety of molecules generally and, in our case, for tobramycin as guest.

Keywords:
nanomaterials; layered double hydroxides; morphology characteristics; drug delivery vectors; antibiotics; bactericidal activity

Issue: 2017, Volume 68, Issue 11

Pages: 2542-2545

Publication date: 2017/12/15

https://doi.org/10.37358/RC.17.11.5924

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
DUCEAC, L.D., STAFIE, L., BANU, E.A., PADURARU, O., CALIN, G., CIUHODARU, M.I., Self-assembled Nanomaterials Type Layered Double Hydroxides Antibiotics Used as Drug Delivery Vectors, Rev. Chim., 68(11), 2017, 2542-2545.

Vancouver
Duceac LD, Stafie L, Banu EA, Paduraru O, Calin G, Ciuhodaru MI. Self-assembled Nanomaterials Type Layered Double Hydroxides Antibiotics Used as Drug Delivery Vectors. Rev. Chim.[internet]. 2017 Nov;68(11):2542-2545. Available from: https://doi.org/10.37358/RC.17.11.5924

APA 6th edition
Duceac, L.D., Stafie, L., Banu, E.A., Paduraru, O., Calin, G. & Ciuhodaru, M.I. (2017). Self-assembled Nanomaterials Type Layered Double Hydroxides Antibiotics Used as Drug Delivery Vectors. Revista de Chimie, 68(11), 2542-2545. https://doi.org/10.37358/RC.17.11.5924

Harvard
Duceac, L.D., Stafie, L., Banu, E.A., Paduraru, O., Calin, G., Ciuhodaru, M.I. (2017). 'Self-assembled Nanomaterials Type Layered Double Hydroxides Antibiotics Used as Drug Delivery Vectors', Revista de Chimie, 68(11), pp. 2542-2545. https://doi.org/10.37358/RC.17.11.5924

IEEE
L.D. Duceac, L. Stafie, E.A. Banu, O. Paduraru, G. Calin, M.I. Ciuhodaru, "Self-assembled Nanomaterials Type Layered Double Hydroxides Antibiotics Used as Drug Delivery Vectors". Revista de Chimie, vol. 68, no. 11, pp. 2542-2545, 2017. [online]. https://doi.org/10.37358/RC.17.11.5924

Text
Letitia Doina Duceac, Liviu Stafie, Elena Ariela Banu, Oana Paduraru, Gabriela Calin, Madalina Irina Ciuhodaru,
Self-assembled Nanomaterials Type Layered Double Hydroxides Antibiotics Used as Drug Delivery Vectors,
Revista de Chimie,
Volume 68, Issue 11,
2017,
Pages 2542-2545,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.11.5924.
(https://revistadechimie.ro/Articles.asp?ID=5924)
Keywords: nanomaterials; layered double hydroxides; morphology characteristics; drug delivery vectors; antibiotics; bactericidal activity

RIS
TY - JOUR
T1 - Self-assembled Nanomaterials Type Layered Double Hydroxides Antibiotics Used as Drug Delivery Vectors
A1 - Duceac, Letitia Doina
A2 - Stafie, Liviu
A3 - Banu, Elena Ariela
A4 - Paduraru, Oana
A5 - Calin, Gabriela
A6 - Ciuhodaru, Madalina Irina
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 11
SP - 2542
EP - 2545
UR - https://doi.org/10.37358/RC.17.11.5924
KW - nanomaterials
KW - layered double hydroxides
KW - morphology characteristics
KW - drug delivery vectors
KW - antibiotics
KW - bactericidal activity
ER -

BibTex
@article{RevCh2017P2542,
author = {Duceac Letitia Doina and Stafie Liviu and Banu Elena Ariela and Paduraru Oana and Calin Gabriela and Ciuhodaru Madalina Irina},
title = {Self-assembled Nanomaterials Type Layered Double Hydroxides Antibiotics Used as Drug Delivery Vectors},
journal = {Revista de Chimie},
volume = {68},
number = {11},
pages = {2542-2545},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.11.5924},
url = {https://revistadechimie.ro/Articles.asp?ID=5924}
}

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