Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery

Budacu, Cristian Constantin; Cioranu, Sorin V. Ibric; Chiscop, Iulia; Mihai, Constantin

Cristian Constantin Budacu, Sorin V. Ibric Cioranu, Iulia Chiscop, Constantin Mihai

Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery

Abstract:

Postoperative manifestations like pain, edema, affected oral functions provoke transitory morbidity in patients to a late recovery. Various classes of medicines are prescribed to prevent placing patients in such unpleasant situations. Both dexamethasone and methylprednisole can be used to reduce the manifestations of the postoperative disease. Although the state of local inflammation is precursory to healing, its exacerbation can lead to extremely painful severe local edema through tissue distention. In the initial phase of the inflammatory process, glucocorticoids act as producers of vein-active substances like prostaglandins and leukins, as dexamethasone has a recognised capacity of reducing COX-2, which is responsible for generating PGs which are produced within the inflammatory response. The efficiency of glucocorticoids is admitted in reducing the inflammatory state, lying at the top of oral maxillofacial surgeons's choice in the therapy of postoperative manifestations. Our research was addressed to a lot of 68 patients to whom we performed interventions of oral and maxillofacial surgery at the Outpatient Clinic of Oral-Maxillofacial Surgery of Ia’i. Dexamethasone is a strong glucocorticoid with the following chemical formula: 90-fluoral-160 methylprednisole. The antiinflamatory effect of a 0.75 mg dosis of dexamethasone is equivalent to that produced by 5 mg of Prednison. Dexamethasone is more efficient than Medrol in the treatment of postoperative edema with complete remission of symptomatology.

Keywords:
oral-maxillofacial surgery; glucocorticoids; dexamethasone; methylprednisole; postoperative disease

Issue: 2017, Volume 68, Issue 11

Pages: 2716-2719

Publication date: 2017/12/15

https://doi.org/10.37358/RC.17.11.5961

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BUDACU, C.C., CIORANU, S.V.I., CHISCOP, I., MIHAI, C., Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery, Rev. Chim., 68(11), 2017, 2716-2719.

Vancouver
Budacu CC, Cioranu SVI, Chiscop I, Mihai C. Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery. Rev. Chim.[internet]. 2017 Nov;68(11):2716-2719. Available from: https://doi.org/10.37358/RC.17.11.5961

APA 6th edition
Budacu, C.C., Cioranu, S.V.I., Chiscop, I. & Mihai, C. (2017). Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery. Revista de Chimie, 68(11), 2716-2719. https://doi.org/10.37358/RC.17.11.5961

Harvard
Budacu, C.C., Cioranu, S.V.I., Chiscop, I., Mihai, C. (2017). 'Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery', Revista de Chimie, 68(11), pp. 2716-2719. https://doi.org/10.37358/RC.17.11.5961

IEEE
C.C. Budacu, S.V.I. Cioranu, I. Chiscop, C. Mihai, "Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery". Revista de Chimie, vol. 68, no. 11, pp. 2716-2719, 2017. [online]. https://doi.org/10.37358/RC.17.11.5961

Text
Cristian Constantin Budacu, Sorin V. Ibric Cioranu, Iulia Chiscop, Constantin Mihai,
Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery,
Revista de Chimie,
Volume 68, Issue 11,
2017,
Pages 2716-2719,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.11.5961.
(https://revistadechimie.ro/Articles.asp?ID=5961)
Keywords: oral-maxillofacial surgery; glucocorticoids; dexamethasone; methylprednisole; postoperative disease

RIS
TY - JOUR
T1 - Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery
A1 - Budacu, Cristian Constantin
A2 - Cioranu, Sorin V. Ibric
A3 - Chiscop, Iulia
A4 - Mihai, Constantin
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 11
SP - 2716
EP - 2719
UR - https://doi.org/10.37358/RC.17.11.5961
KW - oral-maxillofacial surgery
KW - glucocorticoids
KW - dexamethasone
KW - methylprednisole
KW - postoperative disease
ER -

BibTex
@article{RevCh2017P2716,
author = {Budacu Cristian Constantin and Cioranu Sorin V. Ibric and Chiscop Iulia and Mihai Constantin},
title = {Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery},
journal = {Revista de Chimie},
volume = {68},
number = {11},
pages = {2716-2719},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.11.5961},
url = {https://revistadechimie.ro/Articles.asp?ID=5961}
}

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