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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2017, Volume 68, Issue 12, 2907-2913

https://doi.org/10.37358/RC.17.12.6004

Firuta Goga, Edit Forizs, George Borodi, Gheorghe Tomoaia, Alexandra Avram, Reka Balint, Aurora Mocanu, Ossi Horovitz, Maria Tomoaia Cotisel

Behavior of Doped Hydroxyapatites During the Heat Treatment

Abstract:

The goal of this investigation is related to the development of nanostructured biomaterials based on hydroxyapatite (HAP) and multi-doped hydroxyapatites (HAPs), with essential physiological elements, like Mg, Zn, Sr, and Si, for bone repair and regeneration. Nano hydroxyapatites pastes and powders were obtained by wet chemical method using innovative nanotechnology and advanced processing of biomaterials at various temperatures to control the crystallite size and crystallinity degree. The prepared HAPs were analysed by various physical and chemical methods, like SEM, SEM-EDX, AFM, XRD, TG and DSC analysis. The results showed that these biomaterials both in pastes and in powders contained a unique phase, characterized by the HAP structure, which was substantially preserved even at 1000 oC, indicating a high thermal stability of these biomaterials. To enhance their usage, we have prepared HAP and multi-doped HAPs in the form of pastes with controlled humidity (moisture) and powders with controlled crystallinity, which were lyophilized or lyophilized calcined at 300 oC for 1 h. Preliminary biological tests showed that the adhesion and proliferation of human osteoblasts depended on the heat treatment of HAPs used for building the scaffolds. The findings suggest that these biomaterials based on HAPs may have a wide range of medical applications as bone substitute and coatings on metallic implants.
Keywords:
nano hydroxyapatite; doped hydroxyapatites; essential physiological elements; XRD; SEM-EDX; AFM; thermal analysis

Issue: 2017, Volume 68, Issue 12
Pages: 2907-2913
Publication date: 2018/1/15
https://doi.org/10.37358/RC.17.12.6004
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
GOGA, F., FORIZS, E., BORODI, G., TOMOAIA, G., AVRAM, A., BALINT, R., MOCANU, A., HOROVITZ, O., COTISEL, M.T., Behavior of Doped Hydroxyapatites During the Heat Treatment, Rev. Chim., 68(12), 2017, 2907-2913.

Vancouver
Goga F, Forizs E, Borodi G, Tomoaia G, Avram A, Balint R, Mocanu A, Horovitz O, Cotisel MT. Behavior of Doped Hydroxyapatites During the Heat Treatment. Rev. Chim.[internet]. 2017 Dec;68(12):2907-2913. Available from: https://doi.org/10.37358/RC.17.12.6004


APA 6th edition
Goga, F., Forizs, E., Borodi, G., Tomoaia, G., Avram, A., Balint, R.,... Cotisel, M.T. (2017). Behavior of Doped Hydroxyapatites During the Heat Treatment. Revista de Chimie, 68(12), 2907-2913. https://doi.org/10.37358/RC.17.12.6004


Harvard
Goga, F., Forizs, E., Borodi, G., Tomoaia, G., Avram, A., Balint, R., Mocanu, A., Horovitz, O., Cotisel, M.T. (2017). 'Behavior of Doped Hydroxyapatites During the Heat Treatment', Revista de Chimie, 68(12), pp. 2907-2913. https://doi.org/10.37358/RC.17.12.6004


IEEE
F. Goga, E. Forizs, G. Borodi, G. Tomoaia, A. Avram, R. Balint, A. Mocanu, O. Horovitz, M.T. Cotisel, "Behavior of Doped Hydroxyapatites During the Heat Treatment". Revista de Chimie, vol. 68, no. 12, pp. 2907-2913, 2017. [online]. https://doi.org/10.37358/RC.17.12.6004


Text
Firuta Goga, Edit Forizs, George Borodi, Gheorghe Tomoaia, Alexandra Avram, Reka Balint, Aurora Mocanu, Ossi Horovitz, Maria Tomoaia Cotisel,
Behavior of Doped Hydroxyapatites During the Heat Treatment,
Revista de Chimie,
Volume 68, Issue 12,
2017,
Pages 2907-2913,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.12.6004.
(https://revistadechimie.ro/Articles.asp?ID=6004)
Keywords: nano hydroxyapatite; doped hydroxyapatites; essential physiological elements; XRD; SEM-EDX; AFM; thermal analysis


RIS
TY - JOUR
T1 - Behavior of Doped Hydroxyapatites During the Heat Treatment
A1 - Goga, Firuta
A2 - Forizs, Edit
A3 - Borodi, George
A4 - Tomoaia, Gheorghe
A5 - Avram, Alexandra
A6 - Balint, Reka
A7 - Mocanu, Aurora
A8 - Horovitz, Ossi
A9 - Cotisel, Maria Tomoaia
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 12
SP - 2907
EP - 2913
UR - https://doi.org/10.37358/RC.17.12.6004
KW - nano hydroxyapatite
KW - doped hydroxyapatites
KW - essential physiological elements
KW - XRD
KW - SEM-EDX
KW - AFM
KW - thermal analysis
ER -


BibTex
@article{RevCh2017P2907,
author = {Goga Firuta and Forizs Edit and Borodi George and Tomoaia Gheorghe and Avram Alexandra and Balint Reka and Mocanu Aurora and Horovitz Ossi and Cotisel Maria Tomoaia},
title = {Behavior of Doped Hydroxyapatites During the Heat Treatment},
journal = {Revista de Chimie},
volume = {68},
number = {12},
pages = {2907-2913},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.12.6004},
url = {https://revistadechimie.ro/Articles.asp?ID=6004}
}
 
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