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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 2, 371-374

https://doi.org/10.37358/RC.18.2.6109

Delia Hinganu, Marius Valeriu Hinganu, Virgil Bulimar, Dan Andronic

Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis

Abstract:

Establishing the treatment strategy for patients diagnosed with colorectal cancer is based on their imaging and immunohistochemical evaluation. Depending on the stage of tumor invasion and its aggressiveness, is individualized, surgical, oncological, or both treatment. The most important factor for establishing these protocols is the impact of the tumor on intra- and perilesional colorectal vasculature and implicitly on the process of vascular neoformation in the paraneoplastic syndrome. In this regard, we studied a group of patients, colonoscopically diagnosed with colorectal cancer. The study method was to compare the expression of CD34 tumor marker with EMVI (extramural vascular invasion) staging criteria. The results of our study were compared with the intraoperative aspects. In all cases studied tumor extension reached to at least intestinal muscle layer. We conclude that expression of the CD34 marker has always been increased in correlation with EMVI 3-4 stages. In 2 patients with EMVI score 2, the immunohistochemical marker expression was 6% above the maximum threshold. The expression of vascular endothelial proliferation marker is closely correlated with the EMVI score - these values increase proportionally. The use of both criteria for establishing neovasculogenesis, significantly increases the predictability of postoperative progression and long-term survival.
Keywords:
EMVI; immunohistochemistry; CD34; colorectal cancer

Issue: 2018, Volume 69, Issue 2
Pages: 371-374
Publication date: 2018/3/15
https://doi.org/10.37358/RC.18.2.6109
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
HINGANU, D., HINGANU, M.V., BULIMAR, V., ANDRONIC, D., Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis, Rev. Chim., 69(2), 2018, 371-374.

Vancouver
Hinganu D, Hinganu MV, Bulimar V, Andronic D. Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis. Rev. Chim.[internet]. 2018 Feb;69(2):371-374. Available from: https://doi.org/10.37358/RC.18.2.6109


APA 6th edition
Hinganu, D., Hinganu, M.V., Bulimar, V. & Andronic, D. (2018). Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis. Revista de Chimie, 69(2), 371-374. https://doi.org/10.37358/RC.18.2.6109


Harvard
Hinganu, D., Hinganu, M.V., Bulimar, V., Andronic, D. (2018). 'Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis', Revista de Chimie, 69(2), pp. 371-374. https://doi.org/10.37358/RC.18.2.6109


IEEE
D. Hinganu, M.V. Hinganu, V. Bulimar, D. Andronic, "Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis". Revista de Chimie, vol. 69, no. 2, pp. 371-374, 2018. [online]. https://doi.org/10.37358/RC.18.2.6109


Text
Delia Hinganu, Marius Valeriu Hinganu, Virgil Bulimar, Dan Andronic,
Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis,
Revista de Chimie,
Volume 69, Issue 2,
2018,
Pages 371-374,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.2.6109.
(https://revistadechimie.ro/Articles.asp?ID=6109)
Keywords: EMVI; immunohistochemistry; CD34; colorectal cancer


RIS
TY - JOUR
T1 - Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis
A1 - Hinganu, Delia
A2 - Hinganu, Marius Valeriu
A3 - Bulimar, Virgil
A4 - Andronic, Dan
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 2
SP - 371
EP - 374
UR - https://doi.org/10.37358/RC.18.2.6109
KW - EMVI
KW - immunohistochemistry
KW - CD34
KW - colorectal cancer
ER -


BibTex
@article{RevCh2018P371,
author = {Hinganu Delia and Hinganu Marius Valeriu and Bulimar Virgil and Andronic Dan},
title = {Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis},
journal = {Revista de Chimie},
volume = {69},
number = {2},
pages = {371-374},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.2.6109},
url = {https://revistadechimie.ro/Articles.asp?ID=6109}
}
 
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