Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases

Mihai, Catalina; Prelipcean, Cristina Cijevschi; Dranga, Mihaela; Gavrilescu, Otilia; Cardoneanu, Anca; Lacatusu, Cristina; Mihai, Bogdan Mircea

Catalina Mihai, Cristina Cijevschi Prelipcean, Mihaela Dranga, Otilia Gavrilescu, Anca Cardoneanu, Cristina Lacatusu, Bogdan Mircea Mihai

Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases

Abstract:

There is an increasing interest in non-invasive methods to assess gut inflammation. The data regarding the correlations between inflammatory markers and activity of inflammatory bowel disease (IBD) are still controversial. In the last years faecal calprotectin became the most widely used biomarker in diagnosis and monitoring the IBD activity. We prospectively studied the correlation between the serological inflammatory markers (platelets, erythrocyte sedimentation rate - ESR, fibrinogen, C Reactive Protein -CRP, ferritin, albumin), faecal calprotectin and severity of IBD in a tertiary referral centre in North-East Romania. Our study demonstrated that is a good correlation between serologic inflammatory markers (platelets, fibrinogen and ferritin, not ESR and albumin) and severity of IBD. CRP is a good marker in Crohn’s disease (CD) but not in ulcerative colitis (UC). Faecal calprotectin (FC) is the best inflammatory biomarker which correlates with activity both in UC and CD. Inflammatory biomarkers, especially FC are an important tool to evaluate patients with IBD.

Keywords:
Crohn’s disease; ulcerative colitis; inflammatory biomarkers; faecal calprotectin

Issue: 2018, Volume 69, Issue 3

Pages: 710-713

Publication date: 2018/4/15

https://doi.org/10.37358/RC.18.3.6181

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
MIHAI, C., PRELIPCEAN, C.C., DRANGA, M., GAVRILESCU, O., CARDONEANU, A., LACATUSU, C., MIHAI, B.M., Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases, Rev. Chim., 69(3), 2018, 710-713.

Vancouver
Mihai C, Prelipcean CC, Dranga M, Gavrilescu O, Cardoneanu A, Lacatusu C, Mihai BM. Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases. Rev. Chim.[internet]. 2018 Mar;69(3):710-713. Available from: https://doi.org/10.37358/RC.18.3.6181

APA 6th edition
Mihai, C., Prelipcean, C.C., Dranga, M., Gavrilescu, O., Cardoneanu, A., Lacatusu, C. & Mihai, B.M. (2018). Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases. Revista de Chimie, 69(3), 710-713. https://doi.org/10.37358/RC.18.3.6181

Harvard
Mihai, C., Prelipcean, C.C., Dranga, M., Gavrilescu, O., Cardoneanu, A., Lacatusu, C., Mihai, B.M. (2018). 'Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases', Revista de Chimie, 69(3), pp. 710-713. https://doi.org/10.37358/RC.18.3.6181

IEEE
C. Mihai, C.C. Prelipcean, M. Dranga, O. Gavrilescu, A. Cardoneanu, C. Lacatusu, B.M. Mihai, "Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases". Revista de Chimie, vol. 69, no. 3, pp. 710-713, 2018. [online]. https://doi.org/10.37358/RC.18.3.6181

Text
Catalina Mihai, Cristina Cijevschi Prelipcean, Mihaela Dranga, Otilia Gavrilescu, Anca Cardoneanu, Cristina Lacatusu, Bogdan Mircea Mihai,
Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases,
Revista de Chimie,
Volume 69, Issue 3,
2018,
Pages 710-713,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.3.6181.
(https://revistadechimie.ro/Articles.asp?ID=6181)
Keywords: Crohn’s disease; ulcerative colitis; inflammatory biomarkers; faecal calprotectin

RIS
TY - JOUR
T1 - Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases
A1 - Mihai, Catalina
A2 - Prelipcean, Cristina Cijevschi
A3 - Dranga, Mihaela
A4 - Gavrilescu, Otilia
A5 - Cardoneanu, Anca
A6 - Lacatusu, Cristina
A7 - Mihai, Bogdan Mircea
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 3
SP - 710
EP - 713
UR - https://doi.org/10.37358/RC.18.3.6181
KW - Crohn’s disease
KW - ulcerative colitis
KW - inflammatory biomarkers
KW - faecal calprotectin
ER -

BibTex
@article{RevCh2018P710,
author = {Mihai Catalina and Prelipcean Cristina Cijevschi and Dranga Mihaela and Gavrilescu Otilia and Cardoneanu Anca and Lacatusu Cristina and Mihai Bogdan Mircea},
title = {Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases},
journal = {Revista de Chimie},
volume = {69},
number = {3},
pages = {710-713},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.3.6181},
url = {https://revistadechimie.ro/Articles.asp?ID=6181}
}

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