LAVINIA MARIA HOGEA, IOANA TUTA SAS, VLADIMIR POROCH, LAURA ALEXANDRA NUSSBAUM, IOAN SAS, DENIS SERBAN, DRAGOS ERDELEAN, ROXANA FOLESCU, CARMEN LACRAMIOARA ZAMFIR, ANA CRISTINA BREDICEAN, MIHAELA ADRIANA SIMU COMPARATIVE STUDY USING PROGESTERONE AND GYNIPRAL - HEXOPRENALINE SULPHATE, WITH EFFECTS IN POSTPONE PRETERM BIRTH The prevalence of preterm delivery is rising over time. Preterm delivery is a major cause of mortality in infants. In this study, we aimed to compare the frequency of psychological disorders among women with preterm delivery versus term delivery. In this study, psychological disorders in 25 women, who experienced preterm delivery (gestational age of less than 37 weeks) and in 25 women who had term delivery were examined, using Profile of Affective Distress (PAD) and Symptom Checklist-90 questionnaire (SCL-90). Women, who experienced preterm delivery were treated with progesterone from gestational age 24 and Gynipral - Hexoprenaline Sulphate (C22H30N2O10S), 48 hours before birth. The mean age of the participants was 26.26 for women with term delivery and 28.96 in preterm-delivery. The mean (PAD questionnaire) of the participants in the preterm delivery group being higher than that of the term delivery group, indicating a relevant tendency for the women in the first group to experience a strong affective disorder. The mean score of Symptom checklist-90 questionnaire (SCL-90) in women with term delivery was 49.16 (AS = 12.19) and 92.32 (AS = 29.71) in women with preterm delivery (p < 0.001). The results reveal statistically significant differences in the short-term emotional reactions between the two groups of participants. Psychological disorders were higher in women with preterm delivery compared to those with term delivery.