OANA ELENA CIURCANU, VASILICA CRISTESCU, RALUCA DRAGOMIR, VLAD DANILA THE IMPLICATIONS OF HYPERGLYCEMIA IN MAXILO-FACIAL SURGERY In surgical practice, the problems raised by diabetics are extremely complex and require for solving the knowledge of both the physiopathological disorders characteristic of these disease and the changes caused on this pathological field by various dental aggressions. Sometimes, patients with complications of undiagnosed diabetes mellitus are present in the dentistry where all problems of dental and metabolic therapeutics must be solved by the dentist. The lack of knowledge of the general pathophysiology data of the diabetic mellitus disease and of the metabolitical rebalancing methods of these patients on dental aggressions as well as the lack of early knowledge of the events that precede the installation of real metabolic dramas can lead to disaster. The diabetic patient may present in time various dental conditions, some of which are directly or indirectly related to diabetic disease - lesions in the oral cavity are polymorphic and physiologically interpreted in a very different way. The oro-dental changes in diabetes mellitus have as substrate the degenerative arterial involvement in the context of early tissue aging. The hypoglycemia is a factor that makes doctors reluctant to maintain normal blood sugar levels in diabetic anesthetized patients. Hyperglycemia leads to glucosuria, then polyuria, which in turn causes dehydration of the patient through osmotic diuresis. Hyperglycemia decreases the patient’s ability to resist infections.During a period of 6 years, 2011-2016, we observed, treated and monitored a number of 75 patients with diabetes mellitus. Of these, 45 were men and 30 women and the age was between 18-65 years, with the highest incidence between 45-60 years.The importance of diabetic mellitus field in dental practice is not only determined by the high frequency of complications requiring surgery, but also that in these patients any aggression, even limited, can cause entry into a vicious circle where the local lesion aggravates the diabetic state and in turn it worsens the local development of the lesions. The appropriate premedication, protective antibiotic therapy, quality loco-regional anesthesia, rigorous applying of aseptic and antisepsic rules, soft, non-traumatic maneuvers, are mandatory measures addressed to the diabetic patient for performing risk-free surgery.