GEORGETA ZEGAN, LOREDANA GOLOVCENCU, EDUARD RADU CERNEI, ELENA MIHAELA CARAUSU, DANIELA ANISTOROAEI STRUCTURAL AND MORPHOLOGICAL CHARACTERISTICS OF HYBRID NANOMATERIALS TYPE ASCORBIC ACID-HYDROTALCITE USED FOR STIMULATING SALIVARY SECRETION A new hybrid nanomaterial type vitamin C/ZnAl-hydrotalcite, acting as drug delivery system for ascorbic acid, was developed in order to use it for stimulating salivary secretion. The synthesis of this nanomaterial was achieved using a simple coprecipitation method for intercalation of ascorbate anions in the ZnAl-hydrotalcite gallery. The stability of vitamin C was significantly increased after its incorporation into the interlayer space. Structural and morphological characterization techniques revealed an alteration of the pristine nanomaterial type ZnAl-hydrotalcite when vitamin C was loaded in its matrix. Structural and morphological analysis showed that ascorbate anions were intercalated in the interlayer of ZnAl-hydrotalcite having no effect on the hydroxide lattice of hydrotalcite, so this new nanomaterial can be used for the intended purpose.
Keywords: ascorbic acid, hydrotalcite, XRD, SEM, salivary secretion, oral health