Evaluation of the Effects of a Pinus Brutia Bark Extract on Biochemical Parameters and Blood Pressure in an Experimental Arterial Hypertension

Bedreag), Catrinel Florentina Paduraru(Giurescu; Filip, Nina; Trifan, Adriana; Miron, Sorin Dan; Badescu, Codruta; Costache, Irina Iuliana; Namat, Razan Al; Diaconescu, Bogdan; Dumitrescu, Nicoleta; Ciocoiu, Manuela

Catrinel Florentina Paduraru (Giurescu Bedreag), Nina Filip, Adriana Trifan, Sorin Dan Miron, Codruta Badescu, Irina Iuliana Costache, Razan Al Namat, Bogdan Diaconescu, Nicoleta Dumitrescu, Manuela Ciocoiu

Evaluation of the Effects of a Pinus Brutia Bark Extract on Biochemical Parameters and Blood Pressure in an Experimental Arterial Hypertension

Abstract:

The new hypertension therapies which are thought to improve the mechanisms impairing the target organs in arterial hypertension (AHT) would have great practical value. The aim of our study was to investigate the effects of Pinus brutia bark extract (EPb) on serum lipid profiles and oxidative stress in N(G)-Nitro-L-arginine-methyl ester (L-NAME)-induced hypertension. The experiment demonstrated that PbE improved lipid profile and reduced pro-oxidative effects of L-NAME, thus suggesting a possible role of the extract in the management of AHT. Systolic and diastolic blood pressure decrease was significant in the group undergoing simultaneous EPb extract and L-NAME therapy, as compared to the group that was administered only L-NAME. Due to its effects, the Pinus brutia bark extract may be used for the prophylaxis and as adjuvant therapy of cardiovascular conditions.

Keywords:
Pinus Brutia bark extract; oxidative stress; experimental arterial hypertension

Issue: 2018, Volume 69, Issue 7

Pages: 1718-1721

Publication date: 2018/8/15

https://doi.org/10.37358/RC.18.7.6403

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BEDREAG), C.F.P., FILIP, N., TRIFAN, A., MIRON, S.D., BADESCU, C., COSTACHE, I.I., NAMAT, R.A., DIACONESCU, B., DUMITRESCU, N., CIOCOIU, M., Evaluation of the Effects of a Pinus Brutia Bark Extract on Biochemical Parameters and Blood Pressure in an Experimental Arterial Hypertension, Rev. Chim., 69(7), 2018, 1718-1721.

Vancouver
Bedreag) CFP, Filip N, Trifan A, Miron SD, Badescu C, Costache II, Namat RA, Diaconescu B, Dumitrescu N, Ciocoiu M. Evaluation of the Effects of a Pinus Brutia Bark Extract on Biochemical Parameters and Blood Pressure in an Experimental Arterial Hypertension. Rev. Chim.[internet]. 2018 Jul;69(7):1718-1721. Available from: https://doi.org/10.37358/RC.18.7.6403

APA 6th edition
Bedreag), C.F.P., Filip, N., Trifan, A., Miron, S.D., Badescu, C., Costache, I.I.,... Ciocoiu, M. (2018). Evaluation of the Effects of a Pinus Brutia Bark Extract on Biochemical Parameters and Blood Pressure in an Experimental Arterial Hypertension. Revista de Chimie, 69(7), 1718-1721. https://doi.org/10.37358/RC.18.7.6403

Harvard
Bedreag), C.F.P., Filip, N., Trifan, A., Miron, S.D., Badescu, C., Costache, I.I., Namat, R.A., Diaconescu, B., Dumitrescu, N., Ciocoiu, M. (2018). 'Evaluation of the Effects of a Pinus Brutia Bark Extract on Biochemical Parameters and Blood Pressure in an Experimental Arterial Hypertension', Revista de Chimie, 69(7), pp. 1718-1721. https://doi.org/10.37358/RC.18.7.6403

IEEE
C.F.P. Bedreag), N. Filip, A. Trifan, S.D. Miron, C. Badescu, I.I. Costache, R.A. Namat, B. Diaconescu, N. Dumitrescu, M. Ciocoiu, "Evaluation of the Effects of a Pinus Brutia Bark Extract on Biochemical Parameters and Blood Pressure in an Experimental Arterial Hypertension". Revista de Chimie, vol. 69, no. 7, pp. 1718-1721, 2018. [online]. https://doi.org/10.37358/RC.18.7.6403

Text
Catrinel Florentina Paduraru(Giurescu Bedreag), Nina Filip, Adriana Trifan, Sorin Dan Miron, Codruta Badescu, Irina Iuliana Costache, Razan Al Namat, Bogdan Diaconescu, Nicoleta Dumitrescu, Manuela Ciocoiu,
Evaluation of the Effects of a Pinus Brutia Bark Extract on Biochemical Parameters and Blood Pressure in an Experimental Arterial Hypertension,
Revista de Chimie,
Volume 69, Issue 7,
2018,
Pages 1718-1721,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.7.6403.
(https://revistadechimie.ro/Articles.asp?ID=6403)
Keywords: Pinus Brutia bark extract; oxidative stress; experimental arterial hypertension

RIS
TY - JOUR
T1 - Evaluation of the Effects of a Pinus Brutia Bark Extract on Biochemical Parameters and Blood Pressure in an Experimental Arterial Hypertension
A1 - Bedreag), Catrinel Florentina Paduraru(Giurescu
A2 - Filip, Nina
A3 - Trifan, Adriana
A4 - Miron, Sorin Dan
A5 - Badescu, Codruta
A6 - Costache, Irina Iuliana
A7 - Namat, Razan Al
A8 - Diaconescu, Bogdan
A9 - Dumitrescu, Nicoleta
A10 - Ciocoiu, Manuela
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 7
SP - 1718
EP - 1721
UR - https://doi.org/10.37358/RC.18.7.6403
KW - Pinus Brutia bark extract
KW - oxidative stress
KW - experimental arterial hypertension
ER -

BibTex
@article{RevCh2018P1718,
author = {Bedreag) Catrinel Florentina Paduraru(Giurescu and Filip Nina and Trifan Adriana and Miron Sorin Dan and Badescu Codruta and Costache Irina Iuliana and Namat Razan Al and Diaconescu Bogdan and Dumitrescu Nicoleta and Ciocoiu Manuela},
title = {Evaluation of the Effects of a Pinus Brutia Bark Extract on Biochemical Parameters and Blood Pressure in an Experimental Arterial Hypertension},
journal = {Revista de Chimie},
volume = {69},
number = {7},
pages = {1718-1721},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.7.6403},
url = {https://revistadechimie.ro/Articles.asp?ID=6403}
}

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