Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material

Chivu, Manuela; Tantar, Cristian; Hutu, Emilian; Comaneanu, Raluca Monica; Rusu, Elena

Manuela Chivu, Cristian Tantar, Emilian Hutu, Raluca Monica Comaneanu, Elena Rusu

Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material

Abstract:

Bone defects are commonly seen in clinical practice. They are caused by different types of trauma, infections, congenital malformations and cancers. Current approaches to skeletal reconstructive surgery use biomaterials, autografts or allografts. The aim of this study was to analyze bone repair from histologic point of view. To study the repair of bone defects, we used two batches of Wistar mices (Lat Rattus Norvegicus). The 46 subjects under study were divided into two equal lots. In all subjects, a round defect with a diameter of 5 mm was surgically performed on the right and left parietal bone. In the 23 subjects in group I the defect in the left parietal bone was covered with alloplastic material (Osteoset) and the defect in the right parietal bone was not covered with osteoconductive, osteoinductive or osteogenic materials. Regarding subjects in group study II, none of the surgically created bone defects were covered with alloplastic materials. Euthanasia of the subjects included in the study was performed at 2 and 4 months respectively, at the time of surgery. Euthanasia, bone sampling and assembly for microscopic preparations were done on the same day. The histological analysis of a bone repair shows the direct correlation between the healing process and the addition of alloplastic materials (Osteoset).

Keywords:
bone healing; artificial defects; alloplastic material; graft; laboratory animals

Issue: 2018, Volume 69, Issue 7

Pages: 1728-1732

Publication date: 2018/8/15

https://doi.org/10.37358/RC.18.7.6405

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CHIVU, M., TANTAR, C., HUTU, E., COMANEANU, R.M., RUSU, E., Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material, Rev. Chim., 69(7), 2018, 1728-1732.

Vancouver
Chivu M, Tantar C, Hutu E, Comaneanu RM, Rusu E. Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material. Rev. Chim.[internet]. 2018 Jul;69(7):1728-1732. Available from: https://doi.org/10.37358/RC.18.7.6405

APA 6th edition
Chivu, M., Tantar, C., Hutu, E., Comaneanu, R.M. & Rusu, E. (2018). Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material. Revista de Chimie, 69(7), 1728-1732. https://doi.org/10.37358/RC.18.7.6405

Harvard
Chivu, M., Tantar, C., Hutu, E., Comaneanu, R.M., Rusu, E. (2018). 'Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material', Revista de Chimie, 69(7), pp. 1728-1732. https://doi.org/10.37358/RC.18.7.6405

IEEE
M. Chivu, C. Tantar, E. Hutu, R.M. Comaneanu, E. Rusu, "Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material". Revista de Chimie, vol. 69, no. 7, pp. 1728-1732, 2018. [online]. https://doi.org/10.37358/RC.18.7.6405

Text
Manuela Chivu, Cristian Tantar, Emilian Hutu, Raluca Monica Comaneanu, Elena Rusu,
Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material,
Revista de Chimie,
Volume 69, Issue 7,
2018,
Pages 1728-1732,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.7.6405.
(https://revistadechimie.ro/Articles.asp?ID=6405)
Keywords: bone healing; artificial defects; alloplastic material; graft; laboratory animals

RIS
TY - JOUR
T1 - Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material
A1 - Chivu, Manuela
A2 - Tantar, Cristian
A3 - Hutu, Emilian
A4 - Comaneanu, Raluca Monica
A5 - Rusu, Elena
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 7
SP - 1728
EP - 1732
UR - https://doi.org/10.37358/RC.18.7.6405
KW - bone healing
KW - artificial defects
KW - alloplastic material
KW - graft
KW - laboratory animals
ER -

BibTex
@article{RevCh2018P1728,
author = {Chivu Manuela and Tantar Cristian and Hutu Emilian and Comaneanu Raluca Monica and Rusu Elena},
title = {Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material},
journal = {Revista de Chimie},
volume = {69},
number = {7},
pages = {1728-1732},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.7.6405},
url = {https://revistadechimie.ro/Articles.asp?ID=6405}
}

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