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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 8, 2245-2250

https://doi.org/10.37358/RC.18.8.6509

Costin Berceanu, Stefan Paitici, Sabina Berceanu, Elvira Bratila, Anca Maria Ofiteru, Claudia Mehedintu, Sorin Ion Berbece, Dan Navolan, Cosmin Vasile Obleaga, Tudor Adrian Balseanu

Colposcopic, Histologic and Immunohistochemical Assessment in Cervical Intraepithelial Lesions

Abstract:

It is widely accepted that HPV infection precedes the occurrence of neoplastic disease in a varying time frame, and HPV testing can detect 30-100% more cervical precancers than conventional cytology and 20-50% more precancers than liquid-based cytology. Low-grade squamous intraepithelial lesions include the categories of mild dysplasia, respectively cervical intraepithelial neoplasia grade 1, and complementary, various descriptors indicating the presence of Human papilloma virus, such as koilocytotic atypia or condilomatous dysplasia. High-grade squamous intraepithelial lesions cytologically consist of moderate and severe dysplasia, respectively cervical intraepithelial neoplasia grade 2, 3 and carcinoma in situ. The purpose of our paper is to analyze the cytological and colposcopic characteristics in low-grade squamous intraepithelial lesions and high-grade squamous intraepithelial lesions cervical lesions and to accomplish histological and immunohistochemical correlations in these cervical intraepithelial lesions. Systematic three-step colposcopic evaluation using successively, normal saline with or without green filter, acetic acid and Lugol staining provides enhanced efficiency to the colposcopic examination and allows a more individualized and targeted surgical, medical or expectant management. Special microscopic techniques are very important in diagnosing and grading cervical intraepithelial neoplasia.
Keywords:
cervical neoplasia; pathology; surgery; antibody; prognostic marker

Issue: 2018, Volume 69, Issue 8
Pages: 2245-2250
Publication date: 2018/9/15
https://doi.org/10.37358/RC.18.8.6509
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
BERCEANU, C., PAITICI, S., BERCEANU, S., BRATILA, E., OFITERU, A.M., MEHEDINTU, C., BERBECE, S.I., NAVOLAN, D., OBLEAGA, C.V., BALSEANU, T.A., Colposcopic, Histologic and Immunohistochemical Assessment in Cervical Intraepithelial Lesions, Rev. Chim., 69(8), 2018, 2245-2250.

Vancouver
Berceanu C, Paitici S, Berceanu S, Bratila E, Ofiteru AM, Mehedintu C, Berbece SI, Navolan D, Obleaga CV, Balseanu TA. Colposcopic, Histologic and Immunohistochemical Assessment in Cervical Intraepithelial Lesions. Rev. Chim.[internet]. 2018 Aug;69(8):2245-2250. Available from: https://doi.org/10.37358/RC.18.8.6509


APA 6th edition
Berceanu, C., Paitici, S., Berceanu, S., Bratila, E., Ofiteru, A.M., Mehedintu, C.,... Balseanu, T.A. (2018). Colposcopic, Histologic and Immunohistochemical Assessment in Cervical Intraepithelial Lesions. Revista de Chimie, 69(8), 2245-2250. https://doi.org/10.37358/RC.18.8.6509


Harvard
Berceanu, C., Paitici, S., Berceanu, S., Bratila, E., Ofiteru, A.M., Mehedintu, C., Berbece, S.I., Navolan, D., Obleaga, C.V., Balseanu, T.A. (2018). 'Colposcopic, Histologic and Immunohistochemical Assessment in Cervical Intraepithelial Lesions', Revista de Chimie, 69(8), pp. 2245-2250. https://doi.org/10.37358/RC.18.8.6509


IEEE
C. Berceanu, S. Paitici, S. Berceanu, E. Bratila, A.M. Ofiteru, C. Mehedintu, S.I. Berbece, D. Navolan, C.V. Obleaga, T.A. Balseanu, "Colposcopic, Histologic and Immunohistochemical Assessment in Cervical Intraepithelial Lesions". Revista de Chimie, vol. 69, no. 8, pp. 2245-2250, 2018. [online]. https://doi.org/10.37358/RC.18.8.6509


Text
Costin Berceanu, Stefan Paitici, Sabina Berceanu, Elvira Bratila, Anca Maria Ofiteru, Claudia Mehedintu, Sorin Ion Berbece, Dan Navolan, Cosmin Vasile Obleaga, Tudor Adrian Balseanu,
Colposcopic, Histologic and Immunohistochemical Assessment in Cervical Intraepithelial Lesions,
Revista de Chimie,
Volume 69, Issue 8,
2018,
Pages 2245-2250,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.8.6509.
(https://revistadechimie.ro/Articles.asp?ID=6509)
Keywords: cervical neoplasia; pathology; surgery; antibody; prognostic marker


RIS
TY - JOUR
T1 - Colposcopic, Histologic and Immunohistochemical Assessment in Cervical Intraepithelial Lesions
A1 - Berceanu, Costin
A2 - Paitici, Stefan
A3 - Berceanu, Sabina
A4 - Bratila, Elvira
A5 - Ofiteru, Anca Maria
A6 - Mehedintu, Claudia
A7 - Berbece, Sorin Ion
A8 - Navolan, Dan
A9 - Obleaga, Cosmin Vasile
A10 - Balseanu, Tudor Adrian
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 8
SP - 2245
EP - 2250
UR - https://doi.org/10.37358/RC.18.8.6509
KW - cervical neoplasia
KW - pathology
KW - surgery
KW - antibody
KW - prognostic marker
ER -


BibTex
@article{RevCh2018P2245,
author = {Berceanu Costin and Paitici Stefan and Berceanu Sabina and Bratila Elvira and Ofiteru Anca Maria and Mehedintu Claudia and Berbece Sorin Ion and Navolan Dan and Obleaga Cosmin Vasile and Balseanu Tudor Adrian},
title = {Colposcopic, Histologic and Immunohistochemical Assessment in Cervical Intraepithelial Lesions},
journal = {Revista de Chimie},
volume = {69},
number = {8},
pages = {2245-2250},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.8.6509},
url = {https://revistadechimie.ro/Articles.asp?ID=6509}
}
 
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