The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients

Salahoru, Paul; Ghiciuc, Cristina Mihaela; Grigorescu, Cristina; Hinganu, Marius Valeriu; Lupusoru, Catalina Elena

Paul Salahoru, Cristina Mihaela Ghiciuc, Cristina Grigorescu, Marius Valeriu Hinganu, Catalina Elena Lupusoru

The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients

Abstract:

Myasthenia gravis is an autoimmune disorder which presents a series of clinical manifestations which are generally motor. The hallmark of the disorder is muscle weakness, which typically worsens during physical exercise and improves upon rest. Approximatively 80% of the patients presenting this affection test positive for Acetylcholine antibody anti-receptor (AChR-ab).Treatment of patients with myasthenia gravis consists of:administration of oral medica-tion, immunomodulating treatment by removal of AChR-ab through plasmapheresis or surgical intervention (thymectomy).This article presents a retrospective study in which the authors attempted to identify factors which can influence the effect of thymectomy on AChR-ab titration and on the clinical presentation of the patients suffering with myasthenia gravis.

Keywords:
myasthenia gravis; AChR-ab; thymectomy; Acetylcholine

Issue: 2018, Volume 69, Issue 8

Pages: 2251-2253

Publication date: 2018/9/15

https://doi.org/10.37358/RC.18.8.6510

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
SALAHORU, P., GHICIUC, C.M., GRIGORESCU, C., HINGANU, M.V., LUPUSORU, C.E., The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients, Rev. Chim., 69(8), 2018, 2251-2253.

Vancouver
Salahoru P, Ghiciuc CM, Grigorescu C, Hinganu MV, Lupusoru CE. The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients. Rev. Chim.[internet]. 2018 Aug;69(8):2251-2253. Available from: https://doi.org/10.37358/RC.18.8.6510

APA 6th edition
Salahoru, P., Ghiciuc, C.M., Grigorescu, C., Hinganu, M.V. & Lupusoru, C.E. (2018). The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients. Revista de Chimie, 69(8), 2251-2253. https://doi.org/10.37358/RC.18.8.6510

Harvard
Salahoru, P., Ghiciuc, C.M., Grigorescu, C., Hinganu, M.V., Lupusoru, C.E. (2018). 'The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients', Revista de Chimie, 69(8), pp. 2251-2253. https://doi.org/10.37358/RC.18.8.6510

IEEE
P. Salahoru, C.M. Ghiciuc, C. Grigorescu, M.V. Hinganu, C.E. Lupusoru, "The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients". Revista de Chimie, vol. 69, no. 8, pp. 2251-2253, 2018. [online]. https://doi.org/10.37358/RC.18.8.6510

Text
Paul Salahoru, Cristina Mihaela Ghiciuc, Cristina Grigorescu, Marius Valeriu Hinganu, Catalina Elena Lupusoru,
The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients,
Revista de Chimie,
Volume 69, Issue 8,
2018,
Pages 2251-2253,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.8.6510.
(https://revistadechimie.ro/Articles.asp?ID=6510)
Keywords: myasthenia gravis; AChR-ab; thymectomy; Acetylcholine

RIS
TY - JOUR
T1 - The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients
A1 - Salahoru, Paul
A2 - Ghiciuc, Cristina Mihaela
A3 - Grigorescu, Cristina
A4 - Hinganu, Marius Valeriu
A5 - Lupusoru, Catalina Elena
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 8
SP - 2251
EP - 2253
UR - https://doi.org/10.37358/RC.18.8.6510
KW - myasthenia gravis
KW - AChR-ab
KW - thymectomy
KW - Acetylcholine
ER -

BibTex
@article{RevCh2018P2251,
author = {Salahoru Paul and Ghiciuc Cristina Mihaela and Grigorescu Cristina and Hinganu Marius Valeriu and Lupusoru Catalina Elena},
title = {The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients},
journal = {Revista de Chimie},
volume = {69},
number = {8},
pages = {2251-2253},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.8.6510},
url = {https://revistadechimie.ro/Articles.asp?ID=6510}
}

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