Simple Real-time Voltammetric Method for Captopril Determination <br>in Pharmaceutical Formulation

Buleandra, Mihaela; Ciucu, Anton Alexandru; Stefanescu, Dragos Cristian

Mihaela Buleandra, Anton Alexandru Ciucu, Dragos Cristian Stefanescu

Simple Real-time Voltammetric Method for Captopril Determination
in Pharmaceutical Formulation

Abstract:

A novel voltammetric assay for captopril (CAP) determination by using an electrochemically pretreated pencil graphite electrode (PGE*) is presented. The electrochemical oxidation reaction of CAP was investigated with PGE* by using cyclic voltammetry and linear sweep voltammetry techniques. CAP was electrochemically inactive at the non-pretreated pencil graphite electrode surface, while a sharp anodic wave with an anodic peak potential at around 200 mV resulted by using the PGE*. According to kinetic studies upon the electrode behavior, a new reaction mechanism for electrochemical oxidation of captopril is proposed. The sensor was examined as a selective, simple and precise new electrochemical disposable electrode for the determination of CAP in pharmaceutical samples in complex medical cases associated with sleep apnea, with good results.

Keywords:
isposable sensor; dopamine; voltammetry; pharmaceutical samples; sleep apnea

Issue: 2018, Volume 69, Issue 10

Pages: 2858-2862

Publication date: 2018/11/15

https://doi.org/10.37358/RC.18.10.6640

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BULEANDRA, M., CIUCU, A.A., STEFANESCU, D.C., Simple Real-time Voltammetric Method for Captopril Determination
in Pharmaceutical Formulation, Rev. Chim., 69(10), 2018, 2858-2862.

Vancouver
Buleandra M, Ciucu AA, Stefanescu DC. Simple Real-time Voltammetric Method for Captopril Determination
in Pharmaceutical Formulation. Rev. Chim.[internet]. 2018 Oct;69(10):2858-2862. Available from: https://doi.org/10.37358/RC.18.10.6640

APA 6th edition
Buleandra, M., Ciucu, A.A. & Stefanescu, D.C. (2018). Simple Real-time Voltammetric Method for Captopril Determination
in Pharmaceutical Formulation. Revista de Chimie, 69(10), 2858-2862. https://doi.org/10.37358/RC.18.10.6640

Harvard
Buleandra, M., Ciucu, A.A., Stefanescu, D.C. (2018). 'Simple Real-time Voltammetric Method for Captopril Determination
in Pharmaceutical Formulation', Revista de Chimie, 69(10), pp. 2858-2862. https://doi.org/10.37358/RC.18.10.6640

IEEE
M. Buleandra, A.A. Ciucu, D.C. Stefanescu, "Simple Real-time Voltammetric Method for Captopril Determination
in Pharmaceutical Formulation". Revista de Chimie, vol. 69, no. 10, pp. 2858-2862, 2018. [online]. https://doi.org/10.37358/RC.18.10.6640

Text
Mihaela Buleandra, Anton Alexandru Ciucu, Dragos Cristian Stefanescu,
Simple Real-time Voltammetric Method for Captopril Determination
in Pharmaceutical Formulation,
Revista de Chimie,
Volume 69, Issue 10,
2018,
Pages 2858-2862,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.10.6640.
(https://revistadechimie.ro/Articles.asp?ID=6640)
Keywords: isposable sensor; dopamine; voltammetry; pharmaceutical samples; sleep apnea

RIS
TY - JOUR
T1 - Simple Real-time Voltammetric Method for Captopril Determination
in Pharmaceutical Formulation
A1 - Buleandra, Mihaela
A2 - Ciucu, Anton Alexandru
A3 - Stefanescu, Dragos Cristian
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 10
SP - 2858
EP - 2862
UR - https://doi.org/10.37358/RC.18.10.6640
KW - isposable sensor
KW - dopamine
KW - voltammetry
KW - pharmaceutical samples
KW - sleep apnea
ER -

BibTex
@article{RevCh2018P2858,
author = {Buleandra Mihaela and Ciucu Anton Alexandru and Stefanescu Dragos Cristian},
title = {Simple Real-time Voltammetric Method for Captopril Determination
in Pharmaceutical Formulation},
journal = {Revista de Chimie},
volume = {69},
number = {10},
pages = {2858-2862},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.10.6640},
url = {https://revistadechimie.ro/Articles.asp?ID=6640}
}

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