CATALIN DUMITRU, NARCISA CARMEN MLADIN, MARIUS CRAINA, IZABELLA PETRE, LAVINIA CRISTINA MOLERIU, RAZVAN BARDAN, DIANA CAMELIA BONTE, EMIL UNGUREANU, SEBASTIAN AURELIAN STEFANIGA, RAZVAN SUSAN8, ELENA POP, NICOLAE SUCIU CAN BE CONSIDERED THE CA-125 AND NEUTROPHIL-TO-LYMPHOCYTE RATIO VALUES AS A DIAGNOSTIC VALUE IN OVARIAN ENDOMETRIOSIS? In Romania it is estimated that there are half a million patients with endometriosis. The main symptoms are pain (70% of patients with chronic pelvic pain have endometriosis) and infertility (50% of infertile patients have endometriosis). It is difficult to make an accurate diagnosis. Numerous studies show a 7-10-year delay in diagnosis in women in developing countries. 47% of patients should be seen by more than 5 physicians over time until the diagnosis is established. The treatment for endometriosis is the surgical procedure and it is most often performed laparoscopically. The present study was carried in the Obstetrics and Gynecology Departments of the Pius Brinzeu Emergency Clinical Hospital Timisoara. We have included in this study patients who were hospitalized between 2013 and 2017. We have 142 patients who qualified for this study. All the patients had made the same medical tests: we collected information about their age, the neutrophil, lymphocyte and CA125 values, the position of the cyst and the cyst dimension. The aim of this study is to find if there is any association between the CA-125 markers (coelomic epithelial antigen) and the neutrophil-to-lymphocyte ratio in patients who were diagnosed with ovarian endometriosis by transvaginal ultrasound. In all cases the patients underwent laparoscopic surgery. After performing a correlation and regression analysis we obtained that we have a positive strong significant association between the CA 125 values and the ratio values (r=0.94; R2=0.88; p<0.001) . After the surgical excision of endometriosis, CA-125 can be used to monitor the evolution of endometriosis outbreaks, especially when there is a recurring severe pain.