EDWIN SEVER BECHIR, MARA CARSOTE, MIHAELA JANA TUCULINA, MARILENA BATAIOSU, IONELA TEODORA DASCALU, MIHAELA RAESCU, RADU RICA, CONSTANTIN DAGUCI, LUMINITA DAGUCI, ANCA PREDESCU, OANA CELLA ANDREI, RAZVAN MERCUT, CRISTIAN NIKY CUMPATA BIOCHEMICAL ANALYSIS OF MINERAL METABOLISM AND CENTRAL BONE MINERAL DENSITY IN 157 ADULT WOMEN This is a cross-sectional retrospective study of observational type. 157 menopausal subjects were included. A number of N1=89 were younger of 60 years old (also included) and a number of N2=68 were older than 60 years old. Median of age was of 55 years, respective 66 years.The biochemical parameters like total and ionic serum calcium, serum magnesium, and phosphorus between the two groups N1-N2 were similar (p>0.05).The median values of mentioned chemical elements were within normal limits.The bone turnover markers were not statistically significant different between N1 and N2. 25OHD was found deficient in both populations, irrespective of age. DXA- BMD and T-score N1-N2 difference was statistical significant for all the four central sites. Biochemical mineral parameters seem not to be influenced by the cut off of 60 years in menopausal women aged between 40 and 80 years. Yet, a large prevalence of hypovitaminosis D is identified regardless the age without secondary PTH raise. The statistical significant results are for BMD and T-score for all the four central sites.
Keywords: serum calcium, urinary calcium, bone mineral density