CEZAR IONUT CALIN, MARINEL DRIGNEI, STERGIOS GANATSIOS, ERIC JOVENET, GEORGE DINACHE, FLORIN SAVULESCU, DUMITRU FERECHIDE THE ROLE OF OSTEOSYNTHESYS MATERIALS IN THE ETIOPATHOLOGY OF BONE MALIGNANT TUMORS AND RECONSTRUCTION POSSIBILITIES. CASE REPORT The use of osteosynthesis materials in orthopedics is fundamental in the surgical management of patients presenting with various pathologies of the locomotor system, in most cases trauma, but also malign and benign tumors. The risk that these materials could have in inducing malignant transformation of benign tumors or in the onset of primary malignant tumors, was rarely studied. On the one hand, primary malignant tumors of the locomotor system are much less frequent than other kind of neoplasms (for example Ewing sarcoma has an incidence of 1-3 cases / 1.000.000 people / year, ostosarcoma has an incidence of 2 cases / 1.000.000 people / year). On the other hand, usually there is a time window of several years, different from one case to another, from the moment of action of the etiopathogenic factor to the moment of revealing the presence of a neoplastic disease. Based on our clinical practice on a few clinical cases, we intend to study more thoroughly the etiology of primary bone malignant tumors in general and the role of the osteosynthesys materials in this matter especially.
Keywords: osteosynthesis materials, bone malignant tumors