DSC and FT-IR Analysis for the Formulation of Dermal Films with Meloxicam in Bioadhesive Polymeric Matrices

Todoran, Nicoleta; Antonoaea, Paula; Rusu, Aura; Ciurba, Adriana; Birsan, Magdalena; Redai, Emoke

Nicoleta Todoran, Paula Antonoaea, Aura Rusu, Adriana Ciurba, Magdalena Birsan, Emoke Redai

DSC and FT-IR Analysis for the Formulation of Dermal Films with Meloxicam in Bioadhesive Polymeric Matrices

Abstract:

The film forming polymers have a primary role in controlling the diffusion of the drug molecules and the bioavailability, its compatibility with the drug being an essential factor of the formulation. This study aimed the thermal analysis by Differential Scanning Calorimetry (DSC) and Fourier Transform Infrared Spectroscopy (FTIR) evaluation of meloxicam associated with HPMC E5, HPMC 15000 and ethylcellulose, in order to identify the compatibility of associations. The results showed that meloxicam has minor interactions in binary or ternary physical mixtures with the three studied polymers, proving that the mixtures are suitable for obtaining bioadhesive matrices by casting and solvent evaporation method.

Keywords:
meloxicam; ethyl cellulose; infrared; calorimetry

Issue: 2018, Volume 69, Issue 12

Pages: 3692-3697

Publication date: 2019/1/15

https://doi.org/10.37358/RC.18.12.6821

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
TODORAN, N., ANTONOAEA, P., RUSU, A., CIURBA, A., BIRSAN, M., REDAI, E., DSC and FT-IR Analysis for the Formulation of Dermal Films with Meloxicam in Bioadhesive Polymeric Matrices, Rev. Chim., 69(12), 2018, 3692-3697.

Vancouver
Todoran N, Antonoaea P, Rusu A, Ciurba A, Birsan M, Redai E. DSC and FT-IR Analysis for the Formulation of Dermal Films with Meloxicam in Bioadhesive Polymeric Matrices. Rev. Chim.[internet]. 2018 Dec;69(12):3692-3697. Available from: https://doi.org/10.37358/RC.18.12.6821

APA 6th edition
Todoran, N., Antonoaea, P., Rusu, A., Ciurba, A., Birsan, M. & Redai, E. (2018). DSC and FT-IR Analysis for the Formulation of Dermal Films with Meloxicam in Bioadhesive Polymeric Matrices. Revista de Chimie, 69(12), 3692-3697. https://doi.org/10.37358/RC.18.12.6821

Harvard
Todoran, N., Antonoaea, P., Rusu, A., Ciurba, A., Birsan, M., Redai, E. (2018). 'DSC and FT-IR Analysis for the Formulation of Dermal Films with Meloxicam in Bioadhesive Polymeric Matrices', Revista de Chimie, 69(12), pp. 3692-3697. https://doi.org/10.37358/RC.18.12.6821

IEEE
N. Todoran, P. Antonoaea, A. Rusu, A. Ciurba, M. Birsan, E. Redai, "DSC and FT-IR Analysis for the Formulation of Dermal Films with Meloxicam in Bioadhesive Polymeric Matrices". Revista de Chimie, vol. 69, no. 12, pp. 3692-3697, 2018. [online]. https://doi.org/10.37358/RC.18.12.6821

Text
Nicoleta Todoran, Paula Antonoaea, Aura Rusu, Adriana Ciurba, Magdalena Birsan, Emoke Redai,
DSC and FT-IR Analysis for the Formulation of Dermal Films with Meloxicam in Bioadhesive Polymeric Matrices,
Revista de Chimie,
Volume 69, Issue 12,
2018,
Pages 3692-3697,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.12.6821.
(https://revistadechimie.ro/Articles.asp?ID=6821)
Keywords: meloxicam; ethyl cellulose; infrared; calorimetry

RIS
TY - JOUR
T1 - DSC and FT-IR Analysis for the Formulation of Dermal Films with Meloxicam in Bioadhesive Polymeric Matrices
A1 - Todoran, Nicoleta
A2 - Antonoaea, Paula
A3 - Rusu, Aura
A4 - Ciurba, Adriana
A5 - Birsan, Magdalena
A6 - Redai, Emoke
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 12
SP - 3692
EP - 3697
UR - https://doi.org/10.37358/RC.18.12.6821
KW - meloxicam
KW - ethyl cellulose
KW - infrared
KW - calorimetry
ER -

BibTex
@article{RevCh2018P3692,
author = {Todoran Nicoleta and Antonoaea Paula and Rusu Aura and Ciurba Adriana and Birsan Magdalena and Redai Emoke},
title = {DSC and FT-IR Analysis for the Formulation of Dermal Films with Meloxicam in Bioadhesive Polymeric Matrices},
journal = {Revista de Chimie},
volume = {69},
number = {12},
pages = {3692-3697},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.12.6821},
url = {https://revistadechimie.ro/Articles.asp?ID=6821}
}

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