ANIKO MARIA MANEA, DANIELA CIOBOATA, RAMONA STROESCU, MARIOARA BOIA, MARILENA MOTOC BIOCHEMICAL STUDY OF CEREBROSPINAL LIQUID COMPOSITION ON A LOT OF NEWBORNS WITH HYDROCEPHALY Hydrocephaly represents the accumulation of cerebrospinal liquid at cerebral level and it associates with the increasing of intracranial pressure with multiple effects at the level of cerebral tissue. The cerebrospinal fluid (CSF) is a fluid with a clear appearance, with a composition that changes depending on gestational age and associated pathology. Newborns, especially premature, are more susceptible to develop hydrocephaly and a significant percentage out of these will develop neurological deficits and complications associated with ventriculo-peritoneal shunt. The study was carried out in the Department of Neonatology and Premature from the Clinical Emergency Hospital for Children Louis urcanu Timisoara, in a period of 3 years (2014-2016). There were 26 patients included in the study, who presented hydrocephaly diagnosis supported clinically, by ultrasound and CT. There were conducted dosages in dynamics of CSF composition, depending on pathology: malformative, infectious or hemorrhagic.