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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 2, 596-601

https://doi.org/10.37358/RC.19.2.6963

Aqsa Gulzar, Tariq Mahmud, Liviu Mitu, Rubina Munir, Muhammad Imran, Kiran Iftikhar

Synthesis, Characterization and Biological Activities of a Schiff Base Derived from 2-<(1,3-benzothiazol-2-yl)sulfanyl>-N-<4-(hydrazinecarbonyl)phenyl>acetamide and its Complexes
with Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) Ions

Abstract:

A new Schiff base ligand from 2-[(1,3-benzothiazol-2-yl)sulfanyl]-N-[4-(hydrazinecarbonyl)phenyl]acetamide (BHA) and its five metal complexes with transition metal ions [Mn(II), Co(II), Ni(II), Cu(II) and Zn(II)] have been synthesized. The resulting compounds were subsequently characterized by FTIR, UV-Vis, AAS, 1H NMR, 13C NMR and mass spectrometry. The proposed geometries of the Schiff base metal complexes were established on the basis of metal / ligand ratio, through AAS/ICP, electronic spectroscopy and magnetic data. The synthesized Schiff base and its complexes were further investigated for their anti-inflammatory and anticancer activity which exhibited relatively pronounced activity for metal complexes than Schiff base.
Keywords:
Schiff base; metal complexes; anti-inflammatory activity

Issue: 2019, Volume 70, Issue 2
Pages: 596-601
Publication date: 2019/3/15
https://doi.org/10.37358/RC.19.2.6963
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This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
GULZAR, A., MAHMUD, T., MITU, L., MUNIR, R., IMRAN, M., IFTIKHAR, K., Synthesis, Characterization and Biological Activities of a Schiff Base Derived from 2-<(1,3-benzothiazol-2-yl)sulfanyl>-N-<4-(hydrazinecarbonyl)phenyl>acetamide and its Complexes
with Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) Ions, Rev. Chim., 70(2), 2019, 596-601.

Vancouver
Gulzar A, Mahmud T, Mitu L, Munir R, Imran M, Iftikhar K. Synthesis, Characterization and Biological Activities of a Schiff Base Derived from 2-<(1,3-benzothiazol-2-yl)sulfanyl>-N-<4-(hydrazinecarbonyl)phenyl>acetamide and its Complexes
with Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) Ions. Rev. Chim.[internet]. 2019 Feb;70(2):596-601. Available from: https://doi.org/10.37358/RC.19.2.6963


APA 6th edition
Gulzar, A., Mahmud, T., Mitu, L., Munir, R., Imran, M. & Iftikhar, K. (2019). Synthesis, Characterization and Biological Activities of a Schiff Base Derived from 2-<(1,3-benzothiazol-2-yl)sulfanyl>-N-<4-(hydrazinecarbonyl)phenyl>acetamide and its Complexes
with Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) Ions. Revista de Chimie, 70(2), 596-601. https://doi.org/10.37358/RC.19.2.6963


Harvard
Gulzar, A., Mahmud, T., Mitu, L., Munir, R., Imran, M., Iftikhar, K. (2019). 'Synthesis, Characterization and Biological Activities of a Schiff Base Derived from 2-<(1,3-benzothiazol-2-yl)sulfanyl>-N-<4-(hydrazinecarbonyl)phenyl>acetamide and its Complexes
with Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) Ions', Revista de Chimie, 70(2), pp. 596-601. https://doi.org/10.37358/RC.19.2.6963


IEEE
A. Gulzar, T. Mahmud, L. Mitu, R. Munir, M. Imran, K. Iftikhar, "Synthesis, Characterization and Biological Activities of a Schiff Base Derived from 2-<(1,3-benzothiazol-2-yl)sulfanyl>-N-<4-(hydrazinecarbonyl)phenyl>acetamide and its Complexes
with Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) Ions". Revista de Chimie, vol. 70, no. 2, pp. 596-601, 2019. [online]. https://doi.org/10.37358/RC.19.2.6963


Text
Aqsa Gulzar, Tariq Mahmud, Liviu Mitu, Rubina Munir, Muhammad Imran, Kiran Iftikhar,
Synthesis, Characterization and Biological Activities of a Schiff Base Derived from 2-<(1,3-benzothiazol-2-yl)sulfanyl>-N-<4-(hydrazinecarbonyl)phenyl>acetamide and its Complexes
with Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) Ions,
Revista de Chimie,
Volume 70, Issue 2,
2019,
Pages 596-601,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.2.6963.
(https://revistadechimie.ro/Articles.asp?ID=6963)
Keywords: Schiff base; metal complexes; anti-inflammatory activity


RIS
TY - JOUR
T1 - Synthesis, Characterization and Biological Activities of a Schiff Base Derived from 2-<(1,3-benzothiazol-2-yl)sulfanyl>-N-<4-(hydrazinecarbonyl)phenyl>acetamide and its Complexes
with Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) Ions
A1 - Gulzar, Aqsa
A2 - Mahmud, Tariq
A3 - Mitu, Liviu
A4 - Munir, Rubina
A5 - Imran, Muhammad
A6 - Iftikhar, Kiran
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 2
SP - 596
EP - 601
UR - https://doi.org/10.37358/RC.19.2.6963
KW - Schiff base
KW - metal complexes
KW - anti-inflammatory activity
ER -


BibTex
@article{RevCh2019P596,
author = {Gulzar Aqsa and Mahmud Tariq and Mitu Liviu and Munir Rubina and Imran Muhammad and Iftikhar Kiran},
title = {Synthesis, Characterization and Biological Activities of a Schiff Base Derived from 2-<(1,3-benzothiazol-2-yl)sulfanyl>-N-<4-(hydrazinecarbonyl)phenyl>acetamide and its Complexes
with Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) Ions},
journal = {Revista de Chimie},
volume = {70},
number = {2},
pages = {596-601},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.2.6963},
url = {https://revistadechimie.ro/Articles.asp?ID=6963}
}
 
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