Effect of Micotoxins Treatment on Oxidative Stress, Memory and Anxious Behavior in Zebrafish (Danio rerio)

Ciornea, Elena Todirascu; Dumitru, Gabriela; Coprean, Dragomir; Mandalian, Tigran Lucian; Boiangiu, Razvan Stefan; Sandu, Ion; Hritcu, Lucian

Elena Todirascu Ciornea, Gabriela Dumitru, Dragomir Coprean, Tigran Lucian Mandalian, Razvan Stefan Boiangiu, Ion Sandu, Lucian Hritcu

Effect of Micotoxins Treatment on Oxidative Stress, Memory and Anxious Behavior in Zebrafish (Danio rerio)

Abstract:

Natural contaminants, especially mycotoxins, pose a challenge since they are found in a wide range of agricultural crops and differ significantly in chemical structure and symptomatology in humans and signs of disease in animals following exposure to these chemical agents. Mycotoxins are toxic metabolites produced by a diverse group of fungi that contaminate agricultural crops prior to harvest or during storage post-harvest and different species including humans, poultry, swine and fish. Food contamination by mycotoxins is a risk to human and animal health being responsible for significant economic losses and can exhibit a broad range of effects including carcinogenicity, neurotoxicity and developmental toxicity. In the present paper was tested the influence of patulin (PAT, 70 mg/L) and kojic acid (KA, 100, 204 and 284 mg/L) on the activity of antioxidant enzymes (CAT and GPX), MDA (lipid peroxidation marker) but also on memory and anxious behavior in the Danio rerio experimental model.

Keywords:
patulin; kojic acid; memory; behaviour; oxidative stress; zebrafish

Issue: 2019, Volume 70, Issue 3

Pages: 776-780

Publication date: 2019/4/15

https://doi.org/10.37358/RC.19.3.7005

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CIORNEA, E.T., DUMITRU, G., COPREAN, D., MANDALIAN, T.L., BOIANGIU, R.S., SANDU, I., HRITCU, L., Effect of Micotoxins Treatment on Oxidative Stress, Memory and Anxious Behavior in Zebrafish (Danio rerio), Rev. Chim., 70(3), 2019, 776-780.

Vancouver
Ciornea ET, Dumitru G, Coprean D, Mandalian TL, Boiangiu RS, Sandu I, Hritcu L. Effect of Micotoxins Treatment on Oxidative Stress, Memory and Anxious Behavior in Zebrafish (Danio rerio). Rev. Chim.[internet]. 2019 Mar;70(3):776-780. Available from: https://doi.org/10.37358/RC.19.3.7005

APA 6th edition
Ciornea, E.T., Dumitru, G., Coprean, D., Mandalian, T.L., Boiangiu, R.S., Sandu, I. & Hritcu, L. (2019). Effect of Micotoxins Treatment on Oxidative Stress, Memory and Anxious Behavior in Zebrafish (Danio rerio). Revista de Chimie, 70(3), 776-780. https://doi.org/10.37358/RC.19.3.7005

Harvard
Ciornea, E.T., Dumitru, G., Coprean, D., Mandalian, T.L., Boiangiu, R.S., Sandu, I., Hritcu, L. (2019). 'Effect of Micotoxins Treatment on Oxidative Stress, Memory and Anxious Behavior in Zebrafish (Danio rerio)', Revista de Chimie, 70(3), pp. 776-780. https://doi.org/10.37358/RC.19.3.7005

IEEE
E.T. Ciornea, G. Dumitru, D. Coprean, T.L. Mandalian, R.S. Boiangiu, I. Sandu, L. Hritcu, "Effect of Micotoxins Treatment on Oxidative Stress, Memory and Anxious Behavior in Zebrafish (Danio rerio)". Revista de Chimie, vol. 70, no. 3, pp. 776-780, 2019. [online]. https://doi.org/10.37358/RC.19.3.7005

Text
Elena Todirascu Ciornea, Gabriela Dumitru, Dragomir Coprean, Tigran Lucian Mandalian, Razvan Stefan Boiangiu, Ion Sandu, Lucian Hritcu,
Effect of Micotoxins Treatment on Oxidative Stress, Memory and Anxious Behavior in Zebrafish (Danio rerio),
Revista de Chimie,
Volume 70, Issue 3,
2019,
Pages 776-780,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.3.7005.
(https://revistadechimie.ro/Articles.asp?ID=7005)
Keywords: patulin; kojic acid; memory; behaviour; oxidative stress; zebrafish

RIS
TY - JOUR
T1 - Effect of Micotoxins Treatment on Oxidative Stress, Memory and Anxious Behavior in Zebrafish (Danio rerio)
A1 - Ciornea, Elena Todirascu
A2 - Dumitru, Gabriela
A3 - Coprean, Dragomir
A4 - Mandalian, Tigran Lucian
A5 - Boiangiu, Razvan Stefan
A6 - Sandu, Ion
A7 - Hritcu, Lucian
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 3
SP - 776
EP - 780
UR - https://doi.org/10.37358/RC.19.3.7005
KW - patulin
KW - kojic acid
KW - memory
KW - behaviour
KW - oxidative stress
KW - zebrafish
ER -

BibTex
@article{RevCh2019P776,
author = {Ciornea Elena Todirascu and Dumitru Gabriela and Coprean Dragomir and Mandalian Tigran Lucian and Boiangiu Razvan Stefan and Sandu Ion and Hritcu Lucian},
title = {Effect of Micotoxins Treatment on Oxidative Stress, Memory and Anxious Behavior in Zebrafish (Danio rerio)},
journal = {Revista de Chimie},
volume = {70},
number = {3},
pages = {776-780},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.3.7005},
url = {https://revistadechimie.ro/Articles.asp?ID=7005}
}

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