BOGDAN ANDOR, ALINA ANDREEA TISCHER (TUCUINA), DELIA BERCEANU-VADUVA, VOICHITA LAZUREANU, ADELINA CHEVERESAN, MARIOARA POENARU ANTIMICROBIAL ACTIVITY AND CYTOTOXIC EFFECT ON GINGIVAL CELLS OF SILVER NANOPARTICLES OBTAINED BY BIOSYNTHESIS The emergence and development of biofilm is steadily increasing and its currently used prevention and control schemes are free of unwanted effects. Silver nanoparticles obtained through biosynthesis represent an area of interest in the biofilm approach. In the present study, silver nanoparticles were obtained by using the aqueous extract of rosemary leaves which were subsequently tested for antimicrobial activity and for the influence regarding viability of healthy gingival cells. Experiments have shown a significant antimicrobial activity on E. coli, S. aureus, P. aeruginosa and C. albicans. The viability of keratinocytes and gingival fibroblasts was influenced by higher concentrations of test compound (10 and 25 µg/mL).
Keywords: oral diseases, biofilm, green silver nanoparticles, antimicrobial, gingival cells