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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 3, 848-852

https://doi.org/10.37358/RC.19.3.7018

Monica Iliuta Stamate, Lacramioara Ochiuz, Daniel Timofte, Bogdan Ciuntu, Cristina Ghiciuc, Simona Gherman, Alina Stefanache, Ciprian Stamate

Preparation and Pharmaco-Mechanical Characterization of Ketoprofen- Polyvinyl Alcohol Cryogel for Medical Applications

Abstract:

Polyvinyl alcohol is a biocompatible polymer used very commonly both in pharmaceutical and medical fields. Being a water-soluble polymer, it is suitable for the manufacture of hydrogels as well as cryogels used for various medical applications. The present work describes the preparation, structural and physico-mechanical characterization of polyvinyl alcohol cryogels loaded with ketoprofen. By cryogenic technique the polymeric solutions are transformed under certain conditions into porous, elastic and very compressible structures. They are able to absorb a large amount of liquids that they give off by gentle compression. The prepared cryogels were evaluated for different physical, chemical and structural properties, as following: internal morphology, equilibrium swelling ratio and mechanical testing. The cryogel structures show good elasticity and optimal swelling at different temperatures. Due to these properties the studied cryogels are suitable for use in various medical applications involving liquid absorption, mechanical resistance and anti-inflammatory effect.
Keywords:
cryogels; structure; tensile strength; swelling

Issue: 2019, Volume 70, Issue 3
Pages: 848-852
Publication date: 2019/4/15
https://doi.org/10.37358/RC.19.3.7018
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
STAMATE, M.I., OCHIUZ, L., TIMOFTE, D., CIUNTU, B., GHICIUC, C., GHERMAN, S., STEFANACHE, A., STAMATE, C., Preparation and Pharmaco-Mechanical Characterization of Ketoprofen- Polyvinyl Alcohol Cryogel for Medical Applications, Rev. Chim., 70(3), 2019, 848-852.

Vancouver
Stamate MI, Ochiuz L, Timofte D, Ciuntu B, Ghiciuc C, Gherman S, Stefanache A, Stamate C. Preparation and Pharmaco-Mechanical Characterization of Ketoprofen- Polyvinyl Alcohol Cryogel for Medical Applications. Rev. Chim.[internet]. 2019 Mar;70(3):848-852. Available from: https://doi.org/10.37358/RC.19.3.7018


APA 6th edition
Stamate, M.I., Ochiuz, L., Timofte, D., Ciuntu, B., Ghiciuc, C., Gherman, S., Stefanache, A. & Stamate, C. (2019). Preparation and Pharmaco-Mechanical Characterization of Ketoprofen- Polyvinyl Alcohol Cryogel for Medical Applications. Revista de Chimie, 70(3), 848-852. https://doi.org/10.37358/RC.19.3.7018


Harvard
Stamate, M.I., Ochiuz, L., Timofte, D., Ciuntu, B., Ghiciuc, C., Gherman, S., Stefanache, A., Stamate, C. (2019). 'Preparation and Pharmaco-Mechanical Characterization of Ketoprofen- Polyvinyl Alcohol Cryogel for Medical Applications', Revista de Chimie, 70(3), pp. 848-852. https://doi.org/10.37358/RC.19.3.7018


IEEE
M.I. Stamate, L. Ochiuz, D. Timofte, B. Ciuntu, C. Ghiciuc, S. Gherman, A. Stefanache, C. Stamate, "Preparation and Pharmaco-Mechanical Characterization of Ketoprofen- Polyvinyl Alcohol Cryogel for Medical Applications". Revista de Chimie, vol. 70, no. 3, pp. 848-852, 2019. [online]. https://doi.org/10.37358/RC.19.3.7018


Text
Monica Iliuta Stamate, Lacramioara Ochiuz, Daniel Timofte, Bogdan Ciuntu, Cristina Ghiciuc, Simona Gherman, Alina Stefanache, Ciprian Stamate,
Preparation and Pharmaco-Mechanical Characterization of Ketoprofen- Polyvinyl Alcohol Cryogel for Medical Applications,
Revista de Chimie,
Volume 70, Issue 3,
2019,
Pages 848-852,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.3.7018.
(https://revistadechimie.ro/Articles.asp?ID=7018)
Keywords: cryogels; structure; tensile strength; swelling


RIS
TY - JOUR
T1 - Preparation and Pharmaco-Mechanical Characterization of Ketoprofen- Polyvinyl Alcohol Cryogel for Medical Applications
A1 - Stamate, Monica Iliuta
A2 - Ochiuz, Lacramioara
A3 - Timofte, Daniel
A4 - Ciuntu, Bogdan
A5 - Ghiciuc, Cristina
A6 - Gherman, Simona
A7 - Stefanache, Alina
A8 - Stamate, Ciprian
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 3
SP - 848
EP - 852
UR - https://doi.org/10.37358/RC.19.3.7018
KW - cryogels
KW - structure
KW - tensile strength
KW - swelling
ER -


BibTex
@article{RevCh2019P848,
author = {Stamate Monica Iliuta and Ochiuz Lacramioara and Timofte Daniel and Ciuntu Bogdan and Ghiciuc Cristina and Gherman Simona and Stefanache Alina and Stamate Ciprian},
title = {Preparation and Pharmaco-Mechanical Characterization of Ketoprofen- Polyvinyl Alcohol Cryogel for Medical Applications},
journal = {Revista de Chimie},
volume = {70},
number = {3},
pages = {848-852},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.3.7018},
url = {https://revistadechimie.ro/Articles.asp?ID=7018}
}
 
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