ZSOLT GYORI, MONICA SUSAN, RAZVAN SUSAN, ANDRADA IFTODE, CRISTINA TRANDAFIRESCU, ADELINA CHEVERESAN, MIRCEA BERCEANU, GEORGE DRAGHICI, TIBERIU BRATU MELANOMA CELL LINES ROLE IN OBTAINING NEW DRUG CANDIDATES FOR COMBATING THE MALIGNANT PATHOLOGY OF THE CUTANEOUS ORGAN
As prophylactic and therapeutic approaches for melanoma, of great interest and importance are the in vitro studies using cell lines to elucidate several tumoral phenomena. Therefore, the similarities and differences between the different tumor cells must be known and understood in order to obtain a more accurate correlation with processes that occur in vivo. In this study, six cell lines of melanoma, both of mouse and human origin were analyzed from the point of view of cell culture growth, morphology and use in the research of new therapies. In brief, the current paper exhibits a comparison of melanoma cells which can be utilized as a starting point for further in vitro studies and in vivo animal models.
Keywords: melanoma, cells, in vitro, therapy, drugs candidates