NIKOLAOS MAVRITSAKIS, VASILE EMIL URSU, ANCA GANESCU, ELENA IONESCU CLINICAL AND BIOLOGICAL STUDY ON THE RELEVANCE OF HIPERFIBRINOGENEMYME IN CARDIOVASCULAR PATHOLOGY OF THE OBEZ PATIENT
Obesity is a major public health problem, being the second leading cause of death that can be prevented after smoking. Currently, more than 1 billion people have body mass overweight (overweight) and over 300 million suffer from obesity. In the next two decades, the number may double, which will lead to a significant increase in associated pathology, and the average life span of obese patients is 8-10 years shorter than normal subjects <1, 2>. The prevalence of obesity and overweight increases practically in all countries and age groups in the world, and the economic cost of obesity is estimated to be 2-7% of all health expenditure <4>. Adipose tissue, and in particular visceral intraabdominal adipose tissue, is a metabolic active endocrine organ capable of synthesizing and releasing into the blood a wide variety of peptidic and non-peptidic compounds that may play a role in cardiovascular homeostasis.
Keywords obesity, coronary heart disease, hiperfibrinogenemyme, pro-inflammatory status