Biochemical Markers in Nodular Goiter in Children Indications, methods and outcome of the Surgical Treatment

Varcus, Flore; Ciobanu, Gabriela Delia; Grigorovici, Alexandru; Hinganu, Marius Valeriu; Hinganu, Delia; Leustean, Letitia

Flore Varcus, Gabriela Delia Ciobanu, Alexandru Grigorovici, Marius Valeriu Hinganu, Delia Hinganu, Letitia Leustean

Biochemical Markers in Nodular Goiter in Children Indications, methods and outcome of the Surgical Treatment

Abstract:

Nodular goiter is a rare condition in children and adolescents and compared with adults, thyroid nodules are more frequent malignant in pediatric population. We have investigated the prevalence of thyroid carcinoma among the thyroid disorder emphasizing on the surgical treatment in term of indication, methods and complications. Retrospective study of 35 children and adolescents with nodular goiter. Demographic data, thyroid ultrasonographic features, fine needle biopsy aspiration, hormonal profile, surgical treatment procedure as well as histological aspects were recorded. Study included 26 (74%) girls and 9 (26%) boys with a mean age of 11.66 years. Fine needle aspiration biopsy was performed in 10 cases due to the TIRADS score ³ 4 with Bethesda II in 3 cases, Bethesda III in 4 cases and Bethesda V in 3 cases. The surgical treatment was performed in 16 (45.7%) cases due to fine needle aspiration biopsy results or due to the relapse after medical treatment. Lobectomy was performed in 7 (43.7%) cases while total thyroidectomy was the final option for the rest of 9 (56.3%) patients. As a result of pathological examination in 8 cases the thyroid carcinoma has been found. The rest of 8 patients presented benign thyroid findings (follicular adenoma, toxic adenoma and Graves’ disease with follicular adenoma). The prevalence of thyroid carcinoma among the pediatric population with thyroid nodules was 22.8% most affected being the female gender.

Keywords:
thyroid cancer; children; surgery

Issue: 2019, Volume 70, Issue 3

Pages: 996-999

Publication date: 2019/4/15

https://doi.org/10.37358/RC.19.3.7048

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
VARCUS, F., CIOBANU, G.D., GRIGOROVICI, A., HINGANU, M.V., HINGANU, D., LEUSTEAN, L., Biochemical Markers in Nodular Goiter in Children Indications, methods and outcome of the Surgical Treatment, Rev. Chim., 70(3), 2019, 996-999.

Vancouver
Varcus F, Ciobanu GD, Grigorovici A, Hinganu MV, Hinganu D, Leustean L. Biochemical Markers in Nodular Goiter in Children Indications, methods and outcome of the Surgical Treatment. Rev. Chim.[internet]. 2019 Mar;70(3):996-999. Available from: https://doi.org/10.37358/RC.19.3.7048

APA 6th edition
Varcus, F., Ciobanu, G.D., Grigorovici, A., Hinganu, M.V., Hinganu, D. & Leustean, L. (2019). Biochemical Markers in Nodular Goiter in Children Indications, methods and outcome of the Surgical Treatment. Revista de Chimie, 70(3), 996-999. https://doi.org/10.37358/RC.19.3.7048

Harvard
Varcus, F., Ciobanu, G.D., Grigorovici, A., Hinganu, M.V., Hinganu, D., Leustean, L. (2019). 'Biochemical Markers in Nodular Goiter in Children Indications, methods and outcome of the Surgical Treatment', Revista de Chimie, 70(3), pp. 996-999. https://doi.org/10.37358/RC.19.3.7048

IEEE
F. Varcus, G.D. Ciobanu, A. Grigorovici, M.V. Hinganu, D. Hinganu, L. Leustean, "Biochemical Markers in Nodular Goiter in Children Indications, methods and outcome of the Surgical Treatment". Revista de Chimie, vol. 70, no. 3, pp. 996-999, 2019. [online]. https://doi.org/10.37358/RC.19.3.7048

Text
Flore Varcus, Gabriela Delia Ciobanu, Alexandru Grigorovici, Marius Valeriu Hinganu, Delia Hinganu, Letitia Leustean,
Biochemical Markers in Nodular Goiter in Children Indications, methods and outcome of the Surgical Treatment,
Revista de Chimie,
Volume 70, Issue 3,
2019,
Pages 996-999,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.3.7048.
(https://revistadechimie.ro/Articles.asp?ID=7048)
Keywords: thyroid cancer; children; surgery

RIS
TY - JOUR
T1 - Biochemical Markers in Nodular Goiter in Children Indications, methods and outcome of the Surgical Treatment
A1 - Varcus, Flore
A2 - Ciobanu, Gabriela Delia
A3 - Grigorovici, Alexandru
A4 - Hinganu, Marius Valeriu
A5 - Hinganu, Delia
A6 - Leustean, Letitia
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 3
SP - 996
EP - 999
UR - https://doi.org/10.37358/RC.19.3.7048
KW - thyroid cancer
KW - children
KW - surgery
ER -

BibTex
@article{RevCh2019P996,
author = {Varcus Flore and Ciobanu Gabriela Delia and Grigorovici Alexandru and Hinganu Marius Valeriu and Hinganu Delia and Leustean Letitia},
title = {Biochemical Markers in Nodular Goiter in Children Indications, methods and outcome of the Surgical Treatment},
journal = {Revista de Chimie},
volume = {70},
number = {3},
pages = {996-999},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.3.7048},
url = {https://revistadechimie.ro/Articles.asp?ID=7048}
}

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