Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions

Tatu, Alin Laurentiu; Elisei, Alina Mihaela; Lificiu, Oana; Diaconu, Camelia; Miulescu, Magdalena; Buzia, Olimpia Dumitriu

Alin Laurentiu Tatu, Alina Mihaela Elisei, Oana Lificiu, Camelia Diaconu, Magdalena Miulescu, Olimpia Dumitriu Buzia

Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions

Abstract:

The present paper aims at creating a pharmaceutical formulation, i.e. microemulsion with capsaicin as the active principle; the purpose was to solubilize capsaicin and draw up pseudoternary phase diagrams establishing the microemulsion domains. We created a pharmaceutical form: capsaicin ointment, aiming at releasing capsaicin in the microemulsion and ointment bases. Comparative microbiological determinations were performed between microemulsion and ointment. The novelty of the study is formulating microemulsions as a means of solving solubility issues and increasing the bioavailability of medicinal substances.

Keywords:
capsaicina; microemulsion; gram negative germs; gram positive germs

Issue: 2019, Volume 70, Issue 4

Pages: 1278-1282

Publication date: 2019/5/15

https://doi.org/10.37358/RC.19.4.7109

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
TATU, A.L., ELISEI, A.M., LIFICIU, O., DIACONU, C., MIULESCU, M., BUZIA, O.D., Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions, Rev. Chim., 70(4), 2019, 1278-1282.

Vancouver
Tatu AL, Elisei AM, Lificiu O, Diaconu C, Miulescu M, Buzia OD. Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions. Rev. Chim.[internet]. 2019 Apr;70(4):1278-1282. Available from: https://doi.org/10.37358/RC.19.4.7109

APA 6th edition
Tatu, A.L., Elisei, A.M., Lificiu, O., Diaconu, C., Miulescu, M. & Buzia, O.D. (2019). Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions. Revista de Chimie, 70(4), 1278-1282. https://doi.org/10.37358/RC.19.4.7109

Harvard
Tatu, A.L., Elisei, A.M., Lificiu, O., Diaconu, C., Miulescu, M., Buzia, O.D. (2019). 'Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions', Revista de Chimie, 70(4), pp. 1278-1282. https://doi.org/10.37358/RC.19.4.7109

IEEE
A.L. Tatu, A.M. Elisei, O. Lificiu, C. Diaconu, M. Miulescu, O.D. Buzia, "Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions". Revista de Chimie, vol. 70, no. 4, pp. 1278-1282, 2019. [online]. https://doi.org/10.37358/RC.19.4.7109

Text
Alin Laurentiu Tatu, Alina Mihaela Elisei, Oana Lificiu, Camelia Diaconu, Magdalena Miulescu, Olimpia Dumitriu Buzia,
Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions,
Revista de Chimie,
Volume 70, Issue 4,
2019,
Pages 1278-1282,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.4.7109.
(https://revistadechimie.ro/Articles.asp?ID=7109)
Keywords: capsaicina; microemulsion; gram negative germs; gram positive germs

RIS
TY - JOUR
T1 - Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions
A1 - Tatu, Alin Laurentiu
A2 - Elisei, Alina Mihaela
A3 - Lificiu, Oana
A4 - Diaconu, Camelia
A5 - Miulescu, Magdalena
A6 - Buzia, Olimpia Dumitriu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 4
SP - 1278
EP - 1282
UR - https://doi.org/10.37358/RC.19.4.7109
KW - capsaicina
KW - microemulsion
KW - gram negative germs
KW - gram positive germs
ER -

BibTex
@article{RevCh2019P1278,
author = {Tatu Alin Laurentiu and Elisei Alina Mihaela and Lificiu Oana and Diaconu Camelia and Miulescu Magdalena and Buzia Olimpia Dumitriu},
title = {Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions},
journal = {Revista de Chimie},
volume = {70},
number = {4},
pages = {1278-1282},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.4.7109},
url = {https://revistadechimie.ro/Articles.asp?ID=7109}
}

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