OANA CRICIOTOIU, DIANA IULIA STANCA, DANIELA-GABRIELA GLAVAN, CECIL SORIN MIREA, ADRIAN MITA, VERONICA CALBOREAN, VICTOR GHEORMAN, ION UDRISTOIU, ANDA LORENA DIJMARESCU, DRAGOS VIRGIL DAVITOIU, DAN IONUT GHEONEA STATISTICAL ANALYSIS BETWEEN THE ROUTES OF ADMINISTRATION OF L-DOPA AND DIGESTIVE DYSFUNCTIONS IN PARKINSON DISEASE
The aim of this study was to evaluate possible correlation between routes of administration of levodopa in patients diagnosed with Parkinson’s disease and the presence of digestive symptoms. We included in this study 31 patients diagnosed with Parkinson’s disease:14 patients were on oral levodopa and 17 patients were on intrajejunal administration of levodopa/carbidopa. Each patient was assessed using Non-motor Symptoms Questionnaire for Parkinson’s Disease regarding the dysfunction of gastrointestinal tract. The results of our study indicated that there is a different distribution of the digestive dysfunction between the two groups of patients. The study indicate that the constipation was more frequent in those patients with oral medication.