In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains

Ienascu, Ioana Maria Carmen; Obistioiu, Diana; Popescu, Iuliana Maria; Stefanut, Mariana Nela; Gyongyi, Osser; Jurca, Claudia; Ciavoi, Gabriela; Bechir, Edwin Sever; Bechir, Farah; Cata, Adina

Ioana Maria Carmen Ienascu, Diana Obistioiu, Iuliana Maria Popescu, Mariana Nela Stefanut, Osser Gyongyi, Claudia Jurca, Gabriela Ciavoi, Edwin Sever Bechir, Farah Bechir, Adina Cata

In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains

Abstract:

In the dental office, disinfection and sterilization are a matter of utmost importance for both the physician, the medical staff and the patient. Twelve N-(2-bromo-phenyl)-2-hydroxy-benzamide and N-(4-bromo-phenyl)-2-hydroxy-benzamide derivatives were synthesized and tested for antimicrobial activity against 6 bacterial and 2 fungal strains using the Disk diffusion method for susceptibility testing. The obtained results indicated that the N-(2-bromo-phenyl)-2-hydroxy-benzamide derivatives were more active against the tested microbes, inhibition zones of 6-12 mm being obtained, although the most effective compound against S. pyogenes proved to be N-(4-bromo-phenyl)-2-hydroxy-benzamide (14 mm inhibition zone). The tested compounds presented no effect against S. aureus, S. flexneri, S. typhimurium and C. parapsilopsis at the tested concentration.

Keywords:
N-(2-bromo-phenyl)-2-hydroxy-benzamide derivatives; N-(4-bromo-phenyl)-2-hydroxy-benzamide derivatives; antibacterial effect; antifungal effect; disk diffusion method

Issue: 2019, Volume 70, Issue 4

Pages: 1496-1499

Publication date: 2019/5/15

https://doi.org/10.37358/RC.19.4.7157

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
IENASCU, I.M.C., OBISTIOIU, D., POPESCU, I.M., STEFANUT, M.N., GYONGYI, O., JURCA, C., CIAVOI, G., BECHIR, E.S., BECHIR, F., CATA, A., In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains, Rev. Chim., 70(4), 2019, 1496-1499.

Vancouver
Ienascu IMC, Obistioiu D, Popescu IM, Stefanut MN, Gyongyi O, Jurca C, Ciavoi G, Bechir ES, Bechir F, Cata A. In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains. Rev. Chim.[internet]. 2019 Apr;70(4):1496-1499. Available from: https://doi.org/10.37358/RC.19.4.7157

APA 6th edition
Ienascu, I.M.C., Obistioiu, D., Popescu, I.M., Stefanut, M.N., Gyongyi, O., Jurca, C.,... Cata, A. (2019). In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains. Revista de Chimie, 70(4), 1496-1499. https://doi.org/10.37358/RC.19.4.7157

Harvard
Ienascu, I.M.C., Obistioiu, D., Popescu, I.M., Stefanut, M.N., Gyongyi, O., Jurca, C., Ciavoi, G., Bechir, E.S., Bechir, F., Cata, A. (2019). 'In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains', Revista de Chimie, 70(4), pp. 1496-1499. https://doi.org/10.37358/RC.19.4.7157

IEEE
I.M.C. Ienascu, D. Obistioiu, I.M. Popescu, M.N. Stefanut, O. Gyongyi, C. Jurca, G. Ciavoi, E.S. Bechir, F. Bechir, A. Cata, "In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains". Revista de Chimie, vol. 70, no. 4, pp. 1496-1499, 2019. [online]. https://doi.org/10.37358/RC.19.4.7157

Text
Ioana Maria Carmen Ienascu, Diana Obistioiu, Iuliana Maria Popescu, Mariana Nela Stefanut, Osser Gyongyi, Claudia Jurca, Gabriela Ciavoi, Edwin Sever Bechir, Farah Bechir, Adina Cata,
In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains,
Revista de Chimie,
Volume 70, Issue 4,
2019,
Pages 1496-1499,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.4.7157.
(https://revistadechimie.ro/Articles.asp?ID=7157)
Keywords: N-(2-bromo-phenyl)-2-hydroxy-benzamide derivatives; N-(4-bromo-phenyl)-2-hydroxy-benzamide derivatives; antibacterial effect; antifungal effect; disk diffusion method

RIS
TY - JOUR
T1 - In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains
A1 - Ienascu, Ioana Maria Carmen
A2 - Obistioiu, Diana
A3 - Popescu, Iuliana Maria
A4 - Stefanut, Mariana Nela
A5 - Gyongyi, Osser
A6 - Jurca, Claudia
A7 - Ciavoi, Gabriela
A8 - Bechir, Edwin Sever
A9 - Bechir, Farah
A10 - Cata, Adina
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 4
SP - 1496
EP - 1499
UR - https://doi.org/10.37358/RC.19.4.7157
KW - N-(2-bromo-phenyl)-2-hydroxy-benzamide derivatives
KW - N-(4-bromo-phenyl)-2-hydroxy-benzamide derivatives
KW - antibacterial effect
KW - antifungal effect
KW - disk diffusion method
ER -

BibTex
@article{RevCh2019P1496,
author = {Ienascu Ioana Maria Carmen and Obistioiu Diana and Popescu Iuliana Maria and Stefanut Mariana Nela and Gyongyi Osser and Jurca Claudia and Ciavoi Gabriela and Bechir Edwin Sever and Bechir Farah and Cata Adina},
title = {In Vitro Testing of Salicylanilide Derivatives Against Some Fungal and Bacterial Strains},
journal = {Revista de Chimie},
volume = {70},
number = {4},
pages = {1496-1499},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.4.7157},
url = {https://revistadechimie.ro/Articles.asp?ID=7157}
}

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