AMIN BAZYANI, RAZAN AL NAMAT, MAURA GABRIELA FELEA, IRINA IULIANA COSTACHE, MIHAI CONSTANTIN, VICTORITA SORODOC, LAURENTIU SORODOC, PAUL SIMION, MIRELA MIHAELA MIHALCIA, FLORIN MITU, GRIGORE TINICA QRISK2 SCORE IN CABG PATIENTS CORRELATED WITH RISK FACTORS
Guidelines for primary prevention suggested using any risk score, among those QRISK2, identifying the high-risk populations. The purpose of this study was to determine whether the QRISK2 Score would register changes in patients with coronary artery disease demanding acute or postponed CABG intervention. The QRISK2 Score was performed the day of admission after the clinical examination and blood test results, and immediately after CABG surgery (in the first week post-CABG, in an interval of 24 hours to 7 days) having another blood test evaluation. The 120 patients admitted in the Clinic of Cardiovascular Surgery of the Institute of Cardiovascular Disease met the inclusion criteria: CABG patients (less than 1 week), aged 40-85 years old, BMI > 25 kg/m², and mixed dyslipidemia. In both phases, for every patient, it was performed a clinical examination, a set of hematological, biochemical, lipid, coagulation and inflammatory profile, and ECG and echocardiography. Our research on hospitalized patients undergoing CABG, by comparing the Phase I and Phase III results, revealed that the median 10-year QRISK2 cardiovascular risk score was approximately 47.88 % lower (p=0.000) in the first week after cardiac surgery. QRISK2 score gives a more appropriate risk estimation based on the social component, thus identifying high risk patients associating social deprivation. Comparative to Framingham risk score, QRISK2 score, by including additional variables, proves the efficacy of lifestyle changes and management decisions, and sustaines the treatment directed towards modifying variables or risk factors.