The Influence of Diabetes Mellitus on Sodium Homeostasis  in Patients with Preserved Ejection  Fraction Heart Failure

Buse, Alexandru-Madalin; Nanea, Ioan Tiberiu; Nicolae, Camelia; Plesa, Cristina Florentina; Nemes, Roxana Maria; Bisoc, Alina; Diaconu, Magdalena; Paunescu, Alina; Tantu, Monica Marilena

Alexandru-Madalin Buse, Ioan Tiberiu Nanea, Camelia Nicolae, Cristina Florentina Plesa, Roxana Maria Nemes, Alina Bisoc, Magdalena Diaconu, Alina Paunescu, Monica Marilena Tantu

The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure

Abstract:

The objective of the study was to analyze the characteristics of the patients with preserved ejection fraction heart failure (HfpEF) who develop hyponatremia, in relationship with the diabetes mellitus (DM). The current study is an observational retrospective one, that included 36 patients(25 women, 11 men), aged 66.6± 3.1 years, hospitalized for decompensated chronic heart failure, with a left ventricular ejection fraction ]40%. 33% (n=12) of the enrolled patients had hyponatremia, which was strong associated with DM (75% vs 17%, p[0.0005). In hyponatremic patients group was no association between DM and age, gendre, smoking, artrial hypertension, dyslipidemia, ejection fraction distribution or NTproBNP. As for medication at admission, we found an association of the presence of DM with betablockers(100% vs 67%, p[0.05) and with statins( 89% vs 67%, p[0.05). In our study, DM and non-DM patients with low serum sodium values and HfpEF have quite similar clinical profile, since the differences we found do not explain the high prevalence of DM in hyponatremic patients. As a conclusion, the presence of DM itself may explain the high prevalence of DM in hyponatremic patients, but is necessary to have larger studies with more variables included to assess HFpEF patients with DM and hyponatremia.

Keywords:
Hyponatremia diabetes preserved ejection fraction

Issue: 2019, Volume 70, Issue 5

Pages: 1738-1743

Publication date: 2019/6/15

https://doi.org/10.37358/RC.19.5.7205

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BUSE, A., NANEA, I.T., NICOLAE, C., PLESA, C.F., NEMES, R.M., BISOC, A., DIACONU, M., PAUNESCU, A., TANTU, M.M., The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure, Rev. Chim., 70(5), 2019, 1738-1743.

Vancouver
Buse A, Nanea IT, Nicolae C, Plesa CF, Nemes RM, Bisoc A, Diaconu M, Paunescu A, Tantu MM. The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure. Rev. Chim.[internet]. 2019 May;70(5):1738-1743. Available from: https://doi.org/10.37358/RC.19.5.7205

APA 6th edition
Buse, A., Nanea, I.T., Nicolae, C., Plesa, C.F., Nemes, R.M., Bisoc, A.,... Tantu, M.M. (2019). The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure. Revista de Chimie, 70(5), 1738-1743. https://doi.org/10.37358/RC.19.5.7205

Harvard
Buse, A., Nanea, I.T., Nicolae, C., Plesa, C.F., Nemes, R.M., Bisoc, A., Diaconu, M., Paunescu, A., Tantu, M.M. (2019). 'The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure', Revista de Chimie, 70(5), pp. 1738-1743. https://doi.org/10.37358/RC.19.5.7205

IEEE
A. Buse, I.T. Nanea, C. Nicolae, C.F. Plesa, R.M. Nemes, A. Bisoc, M. Diaconu, A. Paunescu, M.M. Tantu, "The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure". Revista de Chimie, vol. 70, no. 5, pp. 1738-1743, 2019. [online]. https://doi.org/10.37358/RC.19.5.7205

Text
Alexandru-Madalin Buse, Ioan Tiberiu Nanea, Camelia Nicolae, Cristina Florentina Plesa, Roxana Maria Nemes, Alina Bisoc, Magdalena Diaconu, Alina Paunescu, Monica Marilena Tantu,
The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure,
Revista de Chimie,
Volume 70, Issue 5,
2019,
Pages 1738-1743,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.5.7205.
(https://revistadechimie.ro/Articles.asp?ID=7205)
Keywords: Hyponatremia diabetes preserved ejection fraction

RIS
TY - JOUR
T1 - The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure
A1 - Buse, Alexandru-Madalin
A2 - Nanea, Ioan Tiberiu
A3 - Nicolae, Camelia
A4 - Plesa, Cristina Florentina
A5 - Nemes, Roxana Maria
A6 - Bisoc, Alina
A7 - Diaconu, Magdalena
A8 - Paunescu, Alina
A9 - Tantu, Monica Marilena
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 5
SP - 1738
EP - 1743
UR - https://doi.org/10.37358/RC.19.5.7205
KW - Hyponatremia diabetes preserved ejection fraction
ER -

BibTex
@article{RevCh2019P1738,
author = {Buse Alexandru-Madalin and Nanea Ioan Tiberiu and Nicolae Camelia and Plesa Cristina Florentina and Nemes Roxana Maria and Bisoc Alina and Diaconu Magdalena and Paunescu Alina and Tantu Monica Marilena},
title = {The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure},
journal = {Revista de Chimie},
volume = {70},
number = {5},
pages = {1738-1743},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.5.7205},
url = {https://revistadechimie.ro/Articles.asp?ID=7205}
}

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