NIKOLAOS MAVRITSAKIS, BOGDAN VIRGIL COTOI, ANCA GANESCU, ELENA IONESCU CLINICAL AND BIOCHEMICAL CORRELATIONS OBESITY - HDL CHOLESTEROL- ISCHEMIC CORONARY HEART DISEASE Central obesity is defined by increasing abdominal circumference ranging from certain limits to the characteristics of the ethnic groups of the rated person (> 94 cm for European males and> 80 cm for Euclid women). The metabolic syndrome, commonly associated with central obesity, must meet at least two of the following four criteria:increased triglyceride levels> 159 mg / dL or specific treatment for this type of dyslipidemia; Low HDL-cholesterol <40 mg / dL or specific treatment for this type of dyslipidemia;Increased blood pressure: Systolic BP ³130 mm Hg or Diastolic BP ³85 mm Hg, or HTA treatment previously diagnosed; High blood glucose level ³100 mg / dL or type 2 diabetes diagnosed previously. HDL-cholesterol (HDL-C) is a group of lipoproteinssynthesized and secreted by hepatocytes. HDL plays an important role in the metabolism of cholesterol, participating in its transport from extrahepatic tissues to the liver for catabolism and excretion.. HDL and LDL participate in maintaining cell cholesterol levels. HDL-cholesterol and apolipoprotein-A values are positive atherosclerosis risk factors. The high level of HDL-C protects the patient, with a low risk of atherosclerosis HDL dosing is done for assessing the risk of coronary artery disease; diagnosis of hyperlipoproteinemia. Increased body weight is associated with increased total mortality and morbidity due to cardiovascular disease, partly mediated by increased blood pressure and cholesterol, lowering HDL-cholesterol and increasing the likelihood of diabetes.