ANDREI VATA, IOANA MARIA HUNEA, OLIVIA DORNEANU, IOANA ALINA HARJA-ALEXA, CLAUDIA PLESCA, GEORGIANA LEONTE-ENACHE, ALEXANDRA CIOCAN, CRISTINA MIHELA GHICIUC, IRINA ESANU, MIHAI MANOLACHE, CATALINA MIHAELA LUCA BIOCHEMICAL CHANGES AND RISK FACTORS IN THE PROGNOSIS OF ANTIBIOTICS SUSCEPTIBILITY IN URINARY TRACT INFECTIONS The aim of our study was evaluation of prevalence of uncomplicated and complicated urinary tract infections (UTIs) among patients with UTIs associated with Gram - negative bacteria and analysis of prognostic risk factors in complicated UTIs. Weretrospectivelyanalyzed the medical records of inpatients with diagnosis of UTI based on clinical, biological and microbiological assay. Susceptibility tests for different antimicrobial categories were performed. Risk factors in complicated UTIs were correlated with pathogens’ susceptibility. A total of 96 eligible patients were analyzed. Complicated UTIs were identified in 66.67% cases. The most frequent uropathogens isolated were E.coli and Klebsiella species. Exrtrarenal factors and nephropathic disease were the most common factors associatedwith an increased prevalence of multi -drug resistant isolates. Knowledge of the spectrum of the possible pathogens and local resistance patterns are very important for the antibacterial treatment outcome.
Keywords: complicated urinary tract infections, risk factors, multi – drug resistance