Thyme Leaves Aqueous Extract and its Formulations. A comparative study based on chemical structures and biological activity

Proks, Maria; Heghes, Alina; Cheveresan, Adelina; Nita, Simona; Voicu, Mirela; Buda, Valentina; Ionescu, Daniela; Nita, Lucian; Trandafirescu, Cristina; Paunescu, Virgil

Maria Proks, Alina Heghes, Adelina Cheveresan, Simona Nita, Mirela Voicu, Valentina Buda, Daniela Ionescu, Lucian Nita, Cristina Trandafirescu, Virgil Paunescu

Thyme Leaves Aqueous Extract and its Formulations. A comparative study based on chemical structures and biological activity

Abstract:

The present study was conducted in order to evaluate the biological activity of thyme aqueous extract as compared to the silver nanoparticles obtained on it on four different cancer lines: non-melanoma skin cancer (A431 cell line), melanoma skin cancer (A375cell line), hormone dependent breast cancer (MCF-7 cell line), and non-hormone dependent breast cancer (MDA-MB-231 cell line). Of particular importance in the study of biological activity is the chemical composition. Formulas rich in compounds of classes like those of flavonoids are recognized for their efficacy and important antioxidant effect. The extract tested at various concentrations ranging from 10-1000 µg/mL exhibited a pronounced effect only on MCF-7 cells at the highest concentration tested and regarding the biosynthesized silver nanoparticles, the effect can be noted even at 1 ì M also only in the case of MCF-7 cells.

Keywords:
thyme aqueous extract; green synthesis; silver; cytotoxicity

Issue: 2019, Volume 70, Issue 5

Pages: 1875-1878

Publication date: 2019/6/15

https://doi.org/10.37358/RC.19.5.7236

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
PROKS, M., HEGHES, A., CHEVERESAN, A., NITA, S., VOICU, M., BUDA, V., IONESCU, D., NITA, L., TRANDAFIRESCU, C., PAUNESCU, V., Thyme Leaves Aqueous Extract and its Formulations. A comparative study based on chemical structures and biological activity, Rev. Chim., 70(5), 2019, 1875-1878.

Vancouver
Proks M, Heghes A, Cheveresan A, Nita S, Voicu M, Buda V, Ionescu D, Nita L, Trandafirescu C, Paunescu V. Thyme Leaves Aqueous Extract and its Formulations. A comparative study based on chemical structures and biological activity. Rev. Chim.[internet]. 2019 May;70(5):1875-1878. Available from: https://doi.org/10.37358/RC.19.5.7236

APA 6th edition
Proks, M., Heghes, A., Cheveresan, A., Nita, S., Voicu, M., Buda, V.,... Paunescu, V. (2019). Thyme Leaves Aqueous Extract and its Formulations. A comparative study based on chemical structures and biological activity. Revista de Chimie, 70(5), 1875-1878. https://doi.org/10.37358/RC.19.5.7236

Harvard
Proks, M., Heghes, A., Cheveresan, A., Nita, S., Voicu, M., Buda, V., Ionescu, D., Nita, L., Trandafirescu, C., Paunescu, V. (2019). 'Thyme Leaves Aqueous Extract and its Formulations. A comparative study based on chemical structures and biological activity', Revista de Chimie, 70(5), pp. 1875-1878. https://doi.org/10.37358/RC.19.5.7236

IEEE
M. Proks, A. Heghes, A. Cheveresan, S. Nita, M. Voicu, V. Buda, D. Ionescu, L. Nita, C. Trandafirescu, V. Paunescu, "Thyme Leaves Aqueous Extract and its Formulations. A comparative study based on chemical structures and biological activity". Revista de Chimie, vol. 70, no. 5, pp. 1875-1878, 2019. [online]. https://doi.org/10.37358/RC.19.5.7236

Text
Maria Proks, Alina Heghes, Adelina Cheveresan, Simona Nita, Mirela Voicu, Valentina Buda, Daniela Ionescu, Lucian Nita, Cristina Trandafirescu, Virgil Paunescu,
Thyme Leaves Aqueous Extract and its Formulations. A comparative study based on chemical structures and biological activity,
Revista de Chimie,
Volume 70, Issue 5,
2019,
Pages 1875-1878,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.5.7236.
(https://revistadechimie.ro/Articles.asp?ID=7236)
Keywords: thyme aqueous extract; green synthesis; silver; cytotoxicity

RIS
TY - JOUR
T1 - Thyme Leaves Aqueous Extract and its Formulations. A comparative study based on chemical structures and biological activity
A1 - Proks, Maria
A2 - Heghes, Alina
A3 - Cheveresan, Adelina
A4 - Nita, Simona
A5 - Voicu, Mirela
A6 - Buda, Valentina
A7 - Ionescu, Daniela
A8 - Nita, Lucian
A9 - Trandafirescu, Cristina
A10 - Paunescu, Virgil
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 5
SP - 1875
EP - 1878
UR - https://doi.org/10.37358/RC.19.5.7236
KW - thyme aqueous extract
KW - green synthesis
KW - silver
KW - cytotoxicity
ER -

BibTex
@article{RevCh2019P1875,
author = {Proks Maria and Heghes Alina and Cheveresan Adelina and Nita Simona and Voicu Mirela and Buda Valentina and Ionescu Daniela and Nita Lucian and Trandafirescu Cristina and Paunescu Virgil},
title = {Thyme Leaves Aqueous Extract and its Formulations. A comparative study based on chemical structures and biological activity},
journal = {Revista de Chimie},
volume = {70},
number = {5},
pages = {1875-1878},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.5.7236},
url = {https://revistadechimie.ro/Articles.asp?ID=7236}
}

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