Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity

Ungur, Rodica; Buzatu, Roxana; Lacatus, Radu; Purdoiu, Robert Cristian; Petrut, Georgiana; Codea, Razvan; Sarpataky, Orsolya; Biris, Alexandra; Popovici, Cristian; Mircean, Mircea; Jivanescu, Delia Bunea; Pestean, Cosmin; Oana, Liviu

Rodica Ungur, Roxana Buzatu, Radu Lacatus, Robert Cristian Purdoiu, Georgiana Petrut, Razvan Codea, Orsolya Sarpataky, Alexandra Biris, Cristian Popovici, Mircea Mircean, Delia Bunea Jivanescu, Cosmin Pestean, Liviu Oana

Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity

Abstract:

Elderflower contains flavonoles, the most important of them being quercetin. These molecules have an important antioxidant effect. The goal of our study was to evaluate which conservation technique of elderflower results the highest concentration of rutin and and phenolic compounds. Further we evaluated the protective effects of these extracts against nephrotoxicity induced by gentamicin in rats. Sambucus nigra extract demonstrates nephroprotective effects in gentamicin-induced renal toxicity, significantly improving outcome and evolution in rats.

Keywords:
elderflowers; rats; gentamycin; nephoprotective effects

Issue: 2019, Volume 70, Issue 6

Pages: 1971-1974

Publication date: 2019/7/15

https://doi.org/10.37358/RC.19.6.7256

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
UNGUR, R., BUZATU, R., LACATUS, R., PURDOIU, R.C., PETRUT, G., CODEA, R., SARPATAKY, O., BIRIS, A., POPOVICI, C., MIRCEAN, M., JIVANESCU, D.B., PESTEAN, C., OANA, L., Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity, Rev. Chim., 70(6), 2019, 1971-1974.

Vancouver
Ungur R, Buzatu R, Lacatus R, Purdoiu RC, Petrut G, Codea R, Sarpataky O, Biris A, Popovici C, Mircean M, Jivanescu DB, Pestean C, Oana L. Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity. Rev. Chim.[internet]. 2019 Jun;70(6):1971-1974. Available from: https://doi.org/10.37358/RC.19.6.7256

APA 6th edition
Ungur, R., Buzatu, R., Lacatus, R., Purdoiu, R.C., Petrut, G., Codea, R.,... Oana, L. (2019). Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity. Revista de Chimie, 70(6), 1971-1974. https://doi.org/10.37358/RC.19.6.7256

Harvard
Ungur, R., Buzatu, R., Lacatus, R., Purdoiu, R.C., Petrut, G., Codea, R., Sarpataky, O., Biris, A., Popovici, C., Mircean, M., Jivanescu, D.B., Pestean, C., Oana, L. (2019). 'Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity', Revista de Chimie, 70(6), pp. 1971-1974. https://doi.org/10.37358/RC.19.6.7256

IEEE
R. Ungur, R. Buzatu, R. Lacatus, R.C. Purdoiu, G. Petrut, R. Codea, O. Sarpataky, A. Biris, C. Popovici, M. Mircean, D.B. Jivanescu, C. Pestean, L. Oana, "Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity". Revista de Chimie, vol. 70, no. 6, pp. 1971-1974, 2019. [online]. https://doi.org/10.37358/RC.19.6.7256

Text
Rodica Ungur, Roxana Buzatu, Radu Lacatus, Robert Cristian Purdoiu, Georgiana Petrut, Razvan Codea, Orsolya Sarpataky, Alexandra Biris, Cristian Popovici, Mircea Mircean, Delia Bunea Jivanescu, Cosmin Pestean, Liviu Oana,
Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity,
Revista de Chimie,
Volume 70, Issue 6,
2019,
Pages 1971-1974,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.6.7256.
(https://revistadechimie.ro/Articles.asp?ID=7256)
Keywords: elderflowers; rats; gentamycin; nephoprotective effects

RIS
TY - JOUR
T1 - Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity
A1 - Ungur, Rodica
A2 - Buzatu, Roxana
A3 - Lacatus, Radu
A4 - Purdoiu, Robert Cristian
A5 - Petrut, Georgiana
A6 - Codea, Razvan
A7 - Sarpataky, Orsolya
A8 - Biris, Alexandra
A9 - Popovici, Cristian
A10 - Mircean, Mircea
A11 - Jivanescu, Delia Bunea
A12 - Pestean, Cosmin
A13 - Oana, Liviu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 6
SP - 1971
EP - 1974
UR - https://doi.org/10.37358/RC.19.6.7256
KW - elderflowers
KW - rats
KW - gentamycin
KW - nephoprotective effects
ER -

BibTex
@article{RevCh2019P1971,
author = {Ungur Rodica and Buzatu Roxana and Lacatus Radu and Purdoiu Robert Cristian and Petrut Georgiana and Codea Razvan and Sarpataky Orsolya and Biris Alexandra and Popovici Cristian and Mircean Mircea and Jivanescu Delia Bunea and Pestean Cosmin and Oana Liviu},
title = {Evaluation of the Nephroprotective Effect of Sambucus Nigra Total Extract in a Rat Experimental Model of Gentamicine Nephrotoxicity},
journal = {Revista de Chimie},
volume = {70},
number = {6},
pages = {1971-1974},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.6.7256},
url = {https://revistadechimie.ro/Articles.asp?ID=7256}
}

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