RODICA UNGUR, ROXANA BUZATU, RADU LACATUS, ROBERT CRISTIAN PURDOIU, GEORGIANA PETRUT, RAZVAN CODEA, ORSOLYA SARPATAKY, ALEXANDRA BIRIS, CRISTIAN POPOVICI, MIRCEA MIRCEAN, DELIA BUNEA JIVANESCU, COSMIN PESTEAN, LIVIU OANA EVALUATION OF THE NEPHROPROTECTIVE EFFECT OF SAMBUCUS NIGRA TOTAL EXTRACT IN A RAT EXPERIMENTAL MODEL OF GENTAMICINE NEPHROTOXICITY Elderflower contains flavonoles, the most important of them being quercetin. These molecules have an important antioxidant effect. The goal of our study was to evaluate which conservation technique of elderflower results the highest concentration of rutin and and phenolic compounds. Further we evaluated the protective effects of these extracts against nephrotoxicity induced by gentamicin in rats. Sambucus nigra extract demonstrates nephroprotective effects in gentamicin-induced renal toxicity, significantly improving outcome and evolution in rats.