ANDREI CRISTIAN LUPU, MIHAELA BOMBOS, GABRIEL VASILIEVICI, LIVIU-DAN MIRON SYNTHESIS AND CHARACTERIZATION OF INCLUSION COMPLEX OF DIMINAZENE ACETURATE WITH B-CICLODEXTRIN Cyclodextrins (CD) are macrocyclic biopolymers with potential applications in the delivery of small and macro-molecular therapeutic agents. Despite the potent host-guest inclusion property, their inherent lack of cellular binding ability has limited applications in drug delivery. Herein, we functionalized b-cyclodextrin (b-CD) with diminazene aceturate(DIMA), which are bioactive molecules, widely distributed some cells, and responsible for antiprotozoal activity. The inclusion complex of DIMA with b-CD was confirmed with textural, thermogravimetric, calorimetric, spectroscopic, and microscopic techniques. Thus, the proposed inclusion complex b-CD-DIMA system could be used as a site-specific drug delivery carrier.