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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 6, 2136-2140

https://doi.org/10.37358/RC.19.6.7291

Andrei Cristian Lupu, Mihaela Bombos, Gabriel Vasilievici, Liviu-Dan Miron

Synthesis and Characterization of Inclusion Complex of Diminazene Aceturate with b-Ciclodextrin

Abstract:

Cyclodextrins (CD) are macrocyclic biopolymers with potential applications in the delivery of small and macro-molecular therapeutic agents. Despite the potent host-guest inclusion property, their inherent lack of cellular binding ability has limited applications in drug delivery. Herein, we functionalized b-cyclodextrin (b-CD) with diminazene aceturate(DIMA), which are bioactive molecules, widely distributed some cells, and responsible for antiprotozoal activity. The inclusion complex of DIMA with b-CD was confirmed with textural, thermogravimetric, calorimetric, spectroscopic, and microscopic techniques. Thus, the proposed inclusion complex b-CD-DIMA system could be used as a site-specific drug delivery carrier.
Keywords:
diminazene aceturate; b-ciclodextrin; inclusion complex

Issue: 2019, Volume 70, Issue 6
Pages: 2136-2140
Publication date: 2019/7/15
https://doi.org/10.37358/RC.19.6.7291
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
LUPU, A.C., BOMBOS, M., VASILIEVICI, G., MIRON, L., Synthesis and Characterization of Inclusion Complex of Diminazene Aceturate with b-Ciclodextrin, Rev. Chim., 70(6), 2019, 2136-2140.

Vancouver
Lupu AC, Bombos M, Vasilievici G, Miron L. Synthesis and Characterization of Inclusion Complex of Diminazene Aceturate with b-Ciclodextrin. Rev. Chim.[internet]. 2019 Jun;70(6):2136-2140. Available from: https://doi.org/10.37358/RC.19.6.7291


APA 6th edition
Lupu, A.C., Bombos, M., Vasilievici, G. & Miron, L. (2019). Synthesis and Characterization of Inclusion Complex of Diminazene Aceturate with b-Ciclodextrin. Revista de Chimie, 70(6), 2136-2140. https://doi.org/10.37358/RC.19.6.7291


Harvard
Lupu, A.C., Bombos, M., Vasilievici, G., Miron, L. (2019). 'Synthesis and Characterization of Inclusion Complex of Diminazene Aceturate with b-Ciclodextrin', Revista de Chimie, 70(6), pp. 2136-2140. https://doi.org/10.37358/RC.19.6.7291


IEEE
A.C. Lupu, M. Bombos, G. Vasilievici, L. Miron, "Synthesis and Characterization of Inclusion Complex of Diminazene Aceturate with b-Ciclodextrin". Revista de Chimie, vol. 70, no. 6, pp. 2136-2140, 2019. [online]. https://doi.org/10.37358/RC.19.6.7291


Text
Andrei Cristian Lupu, Mihaela Bombos, Gabriel Vasilievici, Liviu-Dan Miron,
Synthesis and Characterization of Inclusion Complex of Diminazene Aceturate with b-Ciclodextrin,
Revista de Chimie,
Volume 70, Issue 6,
2019,
Pages 2136-2140,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.6.7291.
(https://revistadechimie.ro/Articles.asp?ID=7291)
Keywords: diminazene aceturate; b-ciclodextrin; inclusion complex


RIS
TY - JOUR
T1 - Synthesis and Characterization of Inclusion Complex of Diminazene Aceturate with b-Ciclodextrin
A1 - Lupu, Andrei Cristian
A2 - Bombos, Mihaela
A3 - Vasilievici, Gabriel
A4 - Miron, Liviu-Dan
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 6
SP - 2136
EP - 2140
UR - https://doi.org/10.37358/RC.19.6.7291
KW - diminazene aceturate
KW - b-ciclodextrin
KW - inclusion complex
ER -


BibTex
@article{RevCh2019P2136,
author = {Lupu Andrei Cristian and Bombos Mihaela and Vasilievici Gabriel and Miron Liviu-Dan},
title = {Synthesis and Characterization of Inclusion Complex of Diminazene Aceturate with b-Ciclodextrin},
journal = {Revista de Chimie},
volume = {70},
number = {6},
pages = {2136-2140},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.6.7291},
url = {https://revistadechimie.ro/Articles.asp?ID=7291}
}
 
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