Portal Vein Thrombosis and Gut Microbiota: Understanding the Burden

Georgescu, Doina; Iurciuc, Mircea; Ionita, Ioana; Georgescu, Liviu-Andrei; Muntean, Mihaela; Lascu, Ana; Ionita, Mihai; Lighezan, Daniel

Doina Georgescu, Mircea Iurciuc, Ioana Ionita, Liviu-Andrei Georgescu, Mihaela Muntean, Ana Lascu, Mihai Ionita, Daniel Lighezan

Portal Vein Thrombosis and Gut Microbiota: Understanding the Burden

Abstract:

Portal vein thrombosis (PVT) continues to be challenging, due to its versatile features and associated clinical pitfalls. This study aimed to explore whether gut microbiota imbalance (GMI) could alter clinical presentation and short term outcome in cirrhotic patients with PVT. We conducted a cross-sectional exploratory study, concerning 50 consecutive cirrhotic patients with PVT recruited during hospitalization. Consecutive to stool microbiological exams, they were assigned into two groups: 25 GMI positive as study group and 25 GMI negative as comparison group. Clinical examination, laboratory work-ups, upper and lower digestive endoscopy, abdominal Duplex ultrasound and CT/MRI were performed Results: Study group displayed significant differences concerning age, interleukin-10 and albumin levels, digestive bleeding, abdominal pain severity and longer hospitalization. In conclusion, dysbiotic patients displayed clinical particularities characterized by older age, higher inflammatory status, hypoalbuminemia, more severe PVT, abdominal pain and digestive bleeding, as well as longer hospitalization duration.

Keywords:
gut microbiota imbalance; liver cirrhosis; portal vein thrombosis

Issue: 2019, Volume 70, Issue 6

Pages: 2181-2185

Publication date: 2019/7/15

https://doi.org/10.37358/RC.19.6.7301

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
GEORGESCU, D., IURCIUC, M., IONITA, I., GEORGESCU, L., MUNTEAN, M., LASCU, A., IONITA, M., LIGHEZAN, D., Portal Vein Thrombosis and Gut Microbiota: Understanding the Burden, Rev. Chim., 70(6), 2019, 2181-2185.

Vancouver
Georgescu D, Iurciuc M, Ionita I, Georgescu L, Muntean M, Lascu A, Ionita M, Lighezan D. Portal Vein Thrombosis and Gut Microbiota: Understanding the Burden. Rev. Chim.[internet]. 2019 Jun;70(6):2181-2185. Available from: https://doi.org/10.37358/RC.19.6.7301

APA 6th edition
Georgescu, D., Iurciuc, M., Ionita, I., Georgescu, L., Muntean, M., Lascu, A., Ionita, M. & Lighezan, D. (2019). Portal Vein Thrombosis and Gut Microbiota: Understanding the Burden. Revista de Chimie, 70(6), 2181-2185. https://doi.org/10.37358/RC.19.6.7301

Harvard
Georgescu, D., Iurciuc, M., Ionita, I., Georgescu, L., Muntean, M., Lascu, A., Ionita, M., Lighezan, D. (2019). 'Portal Vein Thrombosis and Gut Microbiota: Understanding the Burden', Revista de Chimie, 70(6), pp. 2181-2185. https://doi.org/10.37358/RC.19.6.7301

IEEE
D. Georgescu, M. Iurciuc, I. Ionita, L. Georgescu, M. Muntean, A. Lascu, M. Ionita, D. Lighezan, "Portal Vein Thrombosis and Gut Microbiota: Understanding the Burden". Revista de Chimie, vol. 70, no. 6, pp. 2181-2185, 2019. [online]. https://doi.org/10.37358/RC.19.6.7301

Text
Doina Georgescu, Mircea Iurciuc, Ioana Ionita, Liviu-Andrei Georgescu, Mihaela Muntean, Ana Lascu, Mihai Ionita, Daniel Lighezan,
Portal Vein Thrombosis and Gut Microbiota: Understanding the Burden,
Revista de Chimie,
Volume 70, Issue 6,
2019,
Pages 2181-2185,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.6.7301.
(https://revistadechimie.ro/Articles.asp?ID=7301)
Keywords: gut microbiota imbalance; liver cirrhosis; portal vein thrombosis

RIS
TY - JOUR
T1 - Portal Vein Thrombosis and Gut Microbiota: Understanding the Burden
A1 - Georgescu, Doina
A2 - Iurciuc, Mircea
A3 - Ionita, Ioana
A4 - Georgescu, Liviu-Andrei
A5 - Muntean, Mihaela
A6 - Lascu, Ana
A7 - Ionita, Mihai
A8 - Lighezan, Daniel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 6
SP - 2181
EP - 2185
UR - https://doi.org/10.37358/RC.19.6.7301
KW - gut microbiota imbalance
KW - liver cirrhosis
KW - portal vein thrombosis
ER -

BibTex
@article{RevCh2019P2181,
author = {Georgescu Doina and Iurciuc Mircea and Ionita Ioana and Georgescu Liviu-Andrei and Muntean Mihaela and Lascu Ana and Ionita Mihai and Lighezan Daniel},
title = {Portal Vein Thrombosis and Gut Microbiota: Understanding the Burden},
journal = {Revista de Chimie},
volume = {70},
number = {6},
pages = {2181-2185},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.6.7301},
url = {https://revistadechimie.ro/Articles.asp?ID=7301}
}

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