Characterization of Bioactive Compounds from Romanian Cetraria islandica (L) Ach

Patriche, Simona; Ghinea, Ioana Otilia; Adam, Gigi; Gurau, Gabriela; Furdui, Bianca; Dinica, Rodica Mihaela; Rebegea, Laura-Florentina; Lupoae, Mariana

Simona Patriche, Ioana Otilia Ghinea, Gigi Adam, Gabriela Gurau, Bianca Furdui, Rodica Mihaela Dinica, Laura-Florentina Rebegea, Mariana Lupoae

Characterization of Bioactive Compounds from Romanian Cetraria islandica (L) Ach

Abstract:

Lichens (Lichenophyta phylum), the least exploited subdivision of fungus, are composite plants used in folk medicine for the treatment of diverse pathologies, from respiratory to digestive diseases, as they contain over 500 potentially bioactive compounds identified up-to-date. Lichen acids, such as usnic acid, lobar acid, lecanoric acid or salazinic acid, are among these compounds, with biopharmaceutical applications as antimicrobial, antioxidant and cytotoxic agents. The objectives of this study were to extract usnic acid from Romanian Cetraria islandica, (Parmeliaceae family), to characterize the extracts and to evaluate their antioxidant and antimicrobial potential. The extracts were characterized using FTIR spectroscopy and HPTLC techniques. The extracts and pure usnic acid have shown high antioxidant activity and have activity against certain Gram-positive and Gram-negative bacteria and fungi such as Candida albicans. Therefore, the analyzed bioactive compounds could be used as the basis of pharmaceutical formulations to treat various respiratory and digestive disorders.

Keywords:
lichens; usnic acid; IR spectroscopy; HPTLC; antioxidant; antimicrobial

Issue: 2019, Volume 70, Issue 6

Pages: 2186-2191

Publication date: 2019/7/15

https://doi.org/10.37358/RC.19.6.7302

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
PATRICHE, S., GHINEA, I.O., ADAM, G., GURAU, G., FURDUI, B., DINICA, R.M., REBEGEA, L., LUPOAE, M., Characterization of Bioactive Compounds from Romanian Cetraria islandica (L) Ach, Rev. Chim., 70(6), 2019, 2186-2191.

Vancouver
Patriche S, Ghinea IO, Adam G, Gurau G, Furdui B, Dinica RM, Rebegea L, Lupoae M. Characterization of Bioactive Compounds from Romanian Cetraria islandica (L) Ach. Rev. Chim.[internet]. 2019 Jun;70(6):2186-2191. Available from: https://doi.org/10.37358/RC.19.6.7302

APA 6th edition
Patriche, S., Ghinea, I.O., Adam, G., Gurau, G., Furdui, B., Dinica, R.M., Rebegea, L. & Lupoae, M. (2019). Characterization of Bioactive Compounds from Romanian Cetraria islandica (L) Ach. Revista de Chimie, 70(6), 2186-2191. https://doi.org/10.37358/RC.19.6.7302

Harvard
Patriche, S., Ghinea, I.O., Adam, G., Gurau, G., Furdui, B., Dinica, R.M., Rebegea, L., Lupoae, M. (2019). 'Characterization of Bioactive Compounds from Romanian Cetraria islandica (L) Ach', Revista de Chimie, 70(6), pp. 2186-2191. https://doi.org/10.37358/RC.19.6.7302

IEEE
S. Patriche, I.O. Ghinea, G. Adam, G. Gurau, B. Furdui, R.M. Dinica, L. Rebegea, M. Lupoae, "Characterization of Bioactive Compounds from Romanian Cetraria islandica (L) Ach". Revista de Chimie, vol. 70, no. 6, pp. 2186-2191, 2019. [online]. https://doi.org/10.37358/RC.19.6.7302

Text
Simona Patriche, Ioana Otilia Ghinea, Gigi Adam, Gabriela Gurau, Bianca Furdui, Rodica Mihaela Dinica, Laura-Florentina Rebegea, Mariana Lupoae,
Characterization of Bioactive Compounds from Romanian Cetraria islandica (L) Ach,
Revista de Chimie,
Volume 70, Issue 6,
2019,
Pages 2186-2191,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.6.7302.
(https://revistadechimie.ro/Articles.asp?ID=7302)
Keywords: lichens; usnic acid; IR spectroscopy; HPTLC; antioxidant; antimicrobial

RIS
TY - JOUR
T1 - Characterization of Bioactive Compounds from Romanian Cetraria islandica (L) Ach
A1 - Patriche, Simona
A2 - Ghinea, Ioana Otilia
A3 - Adam, Gigi
A4 - Gurau, Gabriela
A5 - Furdui, Bianca
A6 - Dinica, Rodica Mihaela
A7 - Rebegea, Laura-Florentina
A8 - Lupoae, Mariana
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 6
SP - 2186
EP - 2191
UR - https://doi.org/10.37358/RC.19.6.7302
KW - lichens
KW - usnic acid
KW - IR spectroscopy
KW - HPTLC
KW - antioxidant
KW - antimicrobial
ER -

BibTex
@article{RevCh2019P2186,
author = {Patriche Simona and Ghinea Ioana Otilia and Adam Gigi and Gurau Gabriela and Furdui Bianca and Dinica Rodica Mihaela and Rebegea Laura-Florentina and Lupoae Mariana},
title = {Characterization of Bioactive Compounds from Romanian Cetraria islandica (L) Ach},
journal = {Revista de Chimie},
volume = {70},
number = {6},
pages = {2186-2191},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.6.7302},
url = {https://revistadechimie.ro/Articles.asp?ID=7302}
}

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