ANDREI CRISTIAN LUPU, MIHAELA BOMBOS, CRISTIAN ALIN BARBACARIU, CONSTANTIN ROMAN, RALUCA MINDRU, GABRIELA VICTORIA MARTINESCU, LIVIU DAN MIRON CONDITIONING OF PRAZIQUANTEL AND FLORFENICOL FOR SOME HETEROLOGOUS COINFECTIONS OF FARMED CARP
Coinfections can alter the course and severity of different fish diseases. Suspensions of praziquantel (PZQ) and florfenicol (FFC ) based on sunflower oil can be an effective alternative for treating fish coinfections. The use of polyoxyethylene (20) sorbitan monooleate in the presence of ethoxylated castor oil in the preparation of PZQ and FFC suspensions has improved the stability of these suspensions. This PZQ and FFC preparation can be used in the treatment of parasitic/bacterial heterologous coinfections. The suspension of the PZQ and FFC preparation can be administered by water-diffusion, having a controlled release. The compounds are biodegradable and the route of administration remains safe for the environment.