VLAD IMAN, ALINA TACULESCU, CRISTINA DEHELEAN, VIRGIL PAUNESCU MAGNETIC NANOPARTICLES (MNPS) INFLUENCE ON SK-BR3 BREAST CANCER CELL LINE - IN VITRO STUDY
Nanotechnologies involving the use of magnetic nanoparticles made of nickel, iron or cobalt are nowadays developing in anti-tumor therapy and diagnostic. The most important potential of MNPs is for drug delivery, meaning they are functionalized by binding to chemotherapeutic agents, nucleic acids, antibodies, etc. The present study is questioning the possibility of oleic acid-coated iron MNPs to induce cell death per se, selectively in tumor cells (breast cancer adenocarcinoma SK-BR3 cell line) without previous coupling with effector substances.
Keywords: magnetic nanoparticles (MNPs), tumor cells, SK-BR3 cell line, cell death